Dithioerythritol (DTE) is a sulfur containing sugar derived from the corresponding 4-carbon monosaccharide erythrose. It is an epimer of dithiothreitol(DTT).
Dithioerythritol (DTE) is one of two Cleland's Reagents (along with DTT). The two chemicals are epimers of each other, in which the hydroxyl groups of DTE are in the cis form as opposed to the trans form for DTT. DTE is a strong reducing agent and is a component of buffers used in protocols for the isolation and purification of proteins.
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