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产品名称: C1q Protein
产品型号: A400
产品展商: Quidel
美元($)价格: 234.00 元
欧元(€)价格: 0.00 元
人民币(¥)价格: 0.00 元
产品文档: 无相关文档
发布时间:2019-08-23

简单介绍

quidel A400 C1q Protein


C1q Protein  的详细介绍

C1q Protein

For Research Use Only. Not for use in diagnostic procedures.

Purified human complement component C1q. Circulating C1q protein is a hexamer of three unique protein subunits (A, B, and C) with molecular weights of 29, 26 and 22 kD respectively. The assembled hexamer contains a central core or stalk, 6 collagen-like domains and 6 globular protein heads. These globular or terminal regions are responsible for the binding of immunoglobulins (IgM, and IgG). As part of the C1 complex (together with two copies each of C1r and C1s) C1q is central to activation of the classical complement pathway.

All Quidel complement components are tested for functional activity in a standard lytic or applicable functional assay and for biochemical purity by SDS-polyacrylamide gel electrophoresis. Please refer to the Certificate of Analysis for lot specific information on functional titer.

Quidel's purified human complement components are useful in a wide variety of immunochemical and research applications. For assistance with a specific protocol, please contact Quidel Technical Support.

References

Idusogie, E., Presta, L, et al. Mapping of the C1q Binding Site on Rituxan, a chimeric Antibody with a human IgG1 FC, J. Immunol 164:4178-4184, 2000.

Nicholson-Weller, A., Butko, P, Wessels, M. Role of Complement Component C1q in IgG Independent Opsonophagocytosis of Group B Streptococcus, J. Immunol 163:2761-2768, 1999.

Features & Benefits


Feature Benefit
Concentration

1.0 mg/mL

Volume/vial

1.0 mL/vial

Storage

At or below –70°C

Purity

> 95%

Buffer

HEPES, plus 40% glycerol

Ordering Information

Catalog Number Kit Size / Case Size
A400
1.0 mL/vial



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