Anti-Procollagen type IIA N-terminal propeptide (human, PIIANP) BTE 003-02

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产品名称: Anti-Procollagen type IIA N-terminal propeptide (human, PIIANP) BTE 003-02

产品型号: BTE 003-02

产品展商: Bioporto

产品文档: 无相关文档

简单介绍

Anti-Procollagen type IIA N-terminal propeptide (human, PIIANP)

Anti-Procollagen type IIA N-terminal propeptide (human, PIIANP) BTE 003-02 的详细介绍

Cat. No.: BTE 003-02
Product name: Anti-Procollagen type IIA N-terminal propeptide (human, PIIANP)
Description: Mouse monoclonal antibody
Specificity: BTE 003-02 is specific for human PIIANP
Immunogen: Recombinant expressed PIIANP
Application: ELISA, IHC-P
Species reactivity (positive): Human
Species reactivity (negative): Not determined
Subclass: IgG1/k
Gene ID: 1277
Clone number: NA
Epitope: Epitope is located at the amino-terminal part of procollagen type IIA
Content: Available in 200 µL and 1 mL size.1 mg/mL +/- 15%. See Certificate of Analysis for details.
Purification: Protein-A purified
Form: Liquid
Solvent: 0.01 M phosphate buffer, pH 7.4, containing 0.5 M NaCl and 15 mM sodium azide
Storage: 4-8ºC without exposure to light. No precautions necessary during handling.
Target: Collagen type II is the most abundant protein of cartilage matrix. Two isoforms exist and collagen type IIA is involved in early development of cartilage in embryos. The collagen is produced from type II procollagen when two teloterminal propeptides are digested from the procursor and released into the circulation. Procollagen type II N-terminal propeptide (PIIANP) is considered a marker of cartilage synthesis and the normal concentration in serum is approximately 30ng/mL.

Application 1: ELISA
BTE 003-02 also reacts with recombinant PIIANP coated directly onto the microtiter well
Application 2: IHC

BTE 003-02 diluted in 10%FCS/TBS is well suited for immunohistochemistry on formalin-fixed, paraffin-embedded fetal tissue.

Immunohistochemical staining of a formalin-fixed, paraffin-embedded fetal bone anlage in the hand (around week 10) with BTE 003-02.

Immunohistochemical staining of a formalin-fixed, paraffin-embedded biopsy from a chondroblastoma, showing specific staining of tumor cells with AntibodyShop product BTE 003-02 developed with peroxidase-labeled goat anti-mouse Ig (blue color).

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