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ScienCell
重组人骨形成蛋白-2 rhBMP-2
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产品名称:
重组人骨形成蛋白-2 rhBMP-2
产品型号:
108-02
产品展商:
ScienCell
产品文档:
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简单介绍
重组人骨形成蛋白-2 rhBMP-2
重组人骨形成蛋白-2 rhBMP-2
的详细介绍
BMPs (Bone Morphogenetic Proteins) belong to the TGF-beta of signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 is also involved in organogenesis, particularly in cardiac morphogenesis, as well as limb bud formation. BMP-2 expression can be found in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine.The functional form of BMP-2 is a 26 kDa protein composed of two identical 114 amino acid polypeptide chains linked by a single disulfide bond. Each BMP-2 monomer is expressed as the C-terminal part of a precursor polypeptide, which also contains a 23 amino acid signal sequence for secretion, and a 259 amino acid propeptide. After dimerization of this precursor, the covalent bonds between the propeptide (which is also a disulfide-linked homodimer) and the mature BMP-2 ligand are cleaved by a furin-type protease.
货号
108-02
产地
美国
缩写
rhBMP-2
规格
2 μg
用途
科研
储存
-20度
运输
干冰
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