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Rat BioActive Intact PTH ELISA**

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产品名称: Rat BioActive Intact PTH ELISA**
产品型号: 60-2700
产品展商: Quidel
产品文档: 无相关文档

简单介绍

quidel 60-2700 Rat BioActive Intact PTH ELISA**


Rat BioActive Intact PTH ELISA**  的详细介绍

Rat BioActive Intact PTH ELISA

For Research Use Only. Not for use in diagnostic procedures

Rat intact parathyroid hormone (PTH) is an 84 amino acid polypeptide produced by the parathyroid gland with its biological activity residing in the N-terminal region of the peptide. PTH plays an important role in maintaining the concentration of ionized calcium within the limits needed to achieve normal metabolic functions. When serum calcium levels are decreased the parathyroid gland increases secretion of the hormone which results in increased mobilization of calcium from skeletal reserves into the circulation. When levels of serum calcium are increased the secretion of PTH is reduced.

The similarities between rat and human physiology relative to calcium metabolism make rat an excellent live-animal model for studying human skeletal disease and in the pre-clinical evaluation of pharmacologic agents that may alter bone remodeling. Quantitation of only full-length biologically active rat intact PTH with this kit can provide a precise and sensitive assessment of changes in bone and mineral metabolism.

The Rat BioActive Intact PTH ELISA kit is a two-site enzyme-linked immunosorbent assay (ELISA) for the measurement of PTH in rat plasma or cell culture media. Two affinity purified goat polyclonal antibodies have been selected to detect only the full-length biologically active intact form of rat PTH. The antibody which recognizes epitopes within the C-terminal portion of the peptide is biotinylated for capture. The other antibody which recognizes the initial
N-terminal epitope is conjugated with the enzyme horseradish peroxidase (HRP) for detection.

Features & Benefits


Feature Benefit

Product Specifications

Format

ELISA

Tests/kit

96 wells/plate

Sample type

Rat plasma or cell culture media

LOD

3 pg/mL

Incubation time

< 4 hours

Ordering Information

Catalog Number Description Kit Size / Case Size
60-2700

Rat BioActive Intact PTH

96 tests
30-2531

Rat PTH Sample Diluent

10 mL



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