CD86 Antibody

B70, B7-2, LAB72, CD28LG2, FUN-1, BU63.

Rat Anti Mouse Monoclonal.

CD86 type I membrane protein is a member of the immunoglobulin superfamily which is expressed by antigen-presenting cells, and acts as the ligand for two proteins at the cell surface of T cells, CD28 antigen and cytotoxic T-lymphocyte-associated protein 4. CD86 binding with CD28 protein is a co-stimulatory signal for initiation of the T-cell. CD86 binding with CTLA-4 negatively regulates T-cell activation and diminishes the immune response.

mB7-2.

Purified mouse LPS-activated B cells.

Rat IgG2a.

Protein-A.

1mg/ml in PBS (after reconstitution).

Lyophilized: store at 4°C. After reconstitution, if not intended for use within a month, aliquot and store at -20°C.

Reconstitute with of H20. Mix gently, wash the sides of the vial and wait 30-60 seconds before use.

Blocking and staining antibody. For staining, use 10µl/1,000,000 cells. Titer for blocking T cell activation should be determined by the investigator.

This antibody is only available conjugated to Biotin and FITC.

ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.