PyBOP®

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产品名称: PyBOP®

产品型号: KPC-1068-PI

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PyBOP® 的详细介绍

Product Code: KPC-1068-PI
Synonyms/Product Alternate Names: Benzotriazol-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate

Analogue of the BOP coupling reagent which does not form carcinogenic HMPA as by-product. Coupling reactions are rapid, being nearly complete within a few minutes. May be used in place of BOP in peptide synthesis without loss of coupling efficiency. Especially useful for cyclization steps for the activation of hindered amino acid.
Storage Conditions: 2~10° C
Purity: ≥99.0%
Molecular Weight: 520.39
Molecular Formula: C18H28N6OPPF6
CAS Number: [128625-52-5]

J. Putura, P.M. Turunen, M.H. Jäntti, M.E. Ekholm, and J.P. Kukkonen, Neurosci. Lett., 494, 57 (2011). (Pharmacol.)
J. Coste, D. Le-Nguyen, B. Castro, PyBOP®: A new peptide coupling reagent devoid of toxic by-product
S. Asahi, S.-I. Egashira, M. Matsuda, H. Iwaasa, A. Kanatani, M. Ohkubo, M. Ihara, and H. Morishima, Bioorg. Med. Chem. Lett., 13, 111 (2003). (Original; Structure-Activity Relationship & Pharmacol.)

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