Amyloid β-Protein (1-42, O-acyl isopeptide)

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产品名称: Amyloid β-Protein (1-42, O-acyl isopeptide)

产品型号: PAB-AF683

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简单介绍

Amyloid β-Protein (1-42, O-acyl isopeptide) 的详细介绍

Trifluoroacetate
Product Code: PAB-AF683
Synonyms/Product Alternate Names: 26-O-acyl isoAβ1-42, iAβ42, (1-25): Asp-Ala-Glu-Phe-Arg-His-Asp-Ser-Gly-Tyr-Glu-Val-His-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly (26-42): Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-Ile-Ala

For the preparation of Amyloid β-Protein (Human, 1-42) using a pH-induced acyl shift and mitigating aggregation.
Ester bond between Gly²⁵ α-carboxyl group and Ser²⁶ β-hydroxyl group
Storage Conditions: -20 ℃
Purity: ≧90.0% (HPLC)
Molecular Weight: 4514.0
Molecular Formula: C₂₀₃H₃₁₁N₅₅O₆₀S
CAS Number: 753459-14-2

Y. Sohma, M. Sasaki, Y. Hayashi, T. Kimura, and Y. Kiso, Tetrahedron Lett., 45, 5965 (2004). (Original; Chem. Synthesis)
A. Taniguchi, Y. Sohma, Y. Hirayama, H. Mukai, T. Kimura, Y. Hayashi, K. Matsuzaki and Y. Kiso, ChemBioChem, 10, 710 (2009).
R. Roychaudhuri, A. Lomakin, S. Bernstein, X. Zheng, M. M. Condon, G. B. Benedek M. and D. B. Teplow, J. Mol. Biol., 426, 2422 (2014).
T. Yoshiya, T. Uemura, T. Maruno, S. Kubo, Y. Kiso, Y. Sohma, Y. Kobayashi, K. Yoshizawa-Kumagaye, and Y. Nishiuchi, J. Pept. Sci., 20, 669 (2014).
T. Yoshiya, T. Maruno, T. Uemura, S. Kubo, Y. Kiso, Y. Sohma, K. Yoshizawa-Kumagayae, Y. Y. Kobayashi, and Y. Nishiuchi, Bioorg. Med. Chem. Lett., 24, 3861 (2014).

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