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Melittin

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产品名称: Melittin
产品型号: TOX-70001-PI
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简单介绍

Melittin


Melittin  的详细介绍
  • Trifluoroacetate Salt
  • Product Code: TOX-70001-PI
  • Synonyms/Product Alternate Names: H-Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-NH2
  • The major component of bee venom with strong hemolytic activity.  Has been seen to increase insulin secretion via depolarization of pancreatic β-cells. 

  • Origin: Bee (synthetic product)
  • Storage Conditions: -20 ℃
  • Molecular Weight: 2846.53
  • Molecular Formula: C131H229N39O31
  • CAS Number: 20449-79-0
  • One-Letter Code:
    H-GIGAVLKVLTTGLPALISWIKRKRQQ-NH2
  • T.C. Terwilliger and D. Eisenberg, J. Biol. Chem., 257, 6016 (1962). http://www.jbc.org/content/257/11/6016.full.pdf

  • S. Hoissen, et al., J. Chem. (2017). Melittin, a Potential Natural Toxin of Crude Bee Venom: Probable Future Arsenal in the Treatment of Diabetes Mellitus

  • G. Yu, et al., Antimicrob Agents Chemotherapy, 60(3), 1717 (2016). Combination effects of antimicrobial peptides  doi: 10.1128/AAC02434-15.

  • C.A. Rodriguez, et al., Chem Biol., 2, 71 (2014). Covalent modification of a ten-residue cationic antimicrobial peptide with levofloxacin.

  • Y. Fukuyama, et al., Anal Chem.84, 4237 (2012). Alkylated dihydroxybenzoic acid as a MALDI matrix additive for hydrophobic peptide analysis.

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