Cryptdin-4 (Mouse) (0.1 mg vial)

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产品名称: Cryptdin-4 (Mouse) (0.1 mg vial)

产品型号: PDF-4504-s

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Cryptdin-4 (Mouse) (0.1 mg vial) 的详细介绍

Product Code: PDF-4504-s
Synonyms/Product Alternate Names: Crp4; Gly-Leu-Leu-Cys-Tyr-Cys-Arg-Lys-Gly-His-Cys-Lys-Arg-Gly-Glu-Arg-Val-Arg-Gly-Thr-Cys-Gly-Ile-Arg-Phe-Leu-Tyr-Cys-Cys-Pro-Arg-Arg

Antimicrobial Peptide in Paneth Cells
The most potent microbicidal of the mouse Paneth cell α-defensins and is degraded by MMP-7.
Storage Conditions: -20 °C
Molecular Weight: 755.5
Molecular Formula: C₁₅₈H₂₅₇N₅₇O₃₈S₆
Disulfide Bonds: Bonds Between Cys^⁴-Cys^²⁹, Cys^⁶-Cys^²¹, Cys^¹¹-Cys^²⁸
CAS Number: 610309-90-5

M.E. Selsted, S.I. Miller, A.H. Henschen, and A.J. Ouellette, J. Cell Biol., 118, 929 (1992). (Original)
A.J. Ouellette, M.M. Hsieh, M.T. Nosek, D.F. Cano-Gauci, K.M. Huttner, R.N. Buick, and M.E. Selsted, Infect.Immun., 62, 5040 (1994). (Original)
A.J. Ouellette, D. Darmoul, D. Tran, K.M. Huttner, J. Yuan, and M.E. Selsted, Infect.Immun., 67, 6643 (1999). (Chem. Synthesis & Pharmacol.)
W. Jing, H.N. Hunter, H. Tanabe, A.J. Ouellette, and H.J. Vogel, Biochemistry, 43, 15759 (2004). (Solution Structure : NMR)
K. Masuda, N. Sakai, K. Nakamura, S. Yoshioka, and T. Ayabe, J. Innate Immun., 3, 315 (2011). (Pharmacol.)
E. Hayase, D. Hashimoto, K. Nakamura, C. Noizat, R. Ogasawara, S. Takahashi, H. Ohigashi, Y. Yokoi, R. Sugimoto, S. Matsuoka, T. Ara, E. Yokoyama, T. Yamakawa, K. Ebata, T. Kondo, R. Hiramine, T. Aizawa, Y.Ogura, T. Hayashi, H. Mori, K. Kurokawa, K. Tomizuka, T. Ayabe, and T. Teshima, J. Exp. Med., 214, 3507 (2017). (Pharmacol.)

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