μ-Conotoxin SIIA (0.5 mg vial)

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产品名称: μ-Conotoxin SIIA (0.5 mg vial)

产品型号: PCN-4440-v

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简单介绍

μ-Conotoxin SIIA (0.5 mg vial) 的详细介绍

Product Code: PCN-4440-v
Synonyms/Product Alternate Names: Pyr-Asn-Cys-Cys-Asn-Gly-Gly-Cys-Ser-Ser-Lys-Trp-Cys-Arg-Asp-His-Ala-Arg-Cys-Cys-NH2

Tetrodotoxin-Resistant Na+ Channel Blocker with Analgesic Activity
Origin: (Marine Snail, Conus striatus)
Storage Conditions: -20 °C
Molecular Weight: 2207.5
Molecular Formula: C₈₃H₁₂₃N₃₃O₂₇S₆
Disulfide Bonds: (Disulfide bonds between Cys^³-Cys^¹³, Cys^⁴-Cys^¹⁹, and Cys^⁸-Cys^²⁰)

G. Bulaj, P.J. West, J.E. Garrett, M. Marsh, M.-M. Zhang, R.S. Norton, B.J. Smith, D. Yoshikami, and B.M. Olivera, Biochemistry, 44, 7259 (2005). (Original; Primary Structure & Pharmacol.)
S. Yao, M.-M. Zhang, D. Yoshikami, L. Azam, B.M. Olivera, G. Bulaj, and R.S. Norton, Biochemistry, 47, 10940 (2008). (Solution Structure & Pharmacol.)
C.-Z. Wang, H. Zhang, H. Jiang,W. Lu, Z.-Q. Zhao, and C.-W. Chi, Toxicon, 47, 122 (2006). (Pharmacol.)
B.R. Green, P. Catlin, M.-M. Zhang, B. Fiedler, W. Bayudan, A. Morrison, R.S. Norton, B.J. Smith, D. Yoshikami, B.M. Olivera, and G. Bulaj, Chem. Biol., 14, 399 (2007). (Pharmacol.)

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