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Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans

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产品名称: Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans
产品型号: SFQ-3764-PI
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Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans


Dabcyl-Leu-Ala-Gln-Ala-Val-Arg-Ser-Ser-Ser-Arg-Edans  的详细介绍
  • Trifluoroacetate Salt
  • Product Code: SFQ-3764-PI
  • Synonyms/Product Alternate Names: DABCYL-TNF-alpha-EDANS (-4 to +6), human
  • TACE FRET Substrate I

  • TNFa is presumably shed from cell membranes by TNFa-FW, cleaving enzyme (TACE). Incubation of the TACE substrate with recombinant human TACE gives a specific cleavage to restore the quenched fluorescence. The substrate is widely used to screen inhibitors of TNF-α converting enzyme (TACE, ADAM17 endopeptidase) activity. 

  • Storage Conditions: -20 °C
  • Molecular Weight: (M.W. 1573.81)
  • Molecular Formula: C70H104N22O18S
  • CAS Number: 396716-14-6
  • One-Letter Code:
    Dabcyl-LAQAVRSSSR-Edans

  • K.M.Mohler et al., Nature, 370, 218 (1994)

  • A.J.H.Gearing et al., Nature, 370, 555 (1994)

  • B.F.Becker et al., Biol. Chem., 383, 1821 (2002)

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