SNX-482 (0.1mg vial)

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产品名称: SNX-482 (0.1mg vial)

产品型号: PCB-4363-s

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SNX-482 (0.1mg vial) 的详细介绍

Product Code: PCB-4363-s
Synonyms/Product Alternate Names: Gly-Val-Asp-Lys-Ala-Gly-Cys-Arg-Tyr-Met-Phe-Gly-Gly-Cys-Ser-Val-Asn-Asp-Asp-Cys-Cys-Pro-Arg-Leu-Gly-Cys-His-Ser-Leu-Phe-Ser-Tyr-Cys-Ala-Trp-Asp-Leu-Thr-Phe-Ser-Asp

Synthetic Product Class-E (R-Type) Ca2+ Channel Blocker
Origin: (Tarantula, Hysterocrates gigas)
Storage Conditions: -20 °C
Molecular Weight: 4495
Molecular Formula: C₁₉₂H₂₇₄N₅₂O₆₀S₇
Disulfide Bonds: (Disulfide bonds between Cys⁷-Cys²¹, Cys¹⁴-Cys²⁶, and Cys²⁰-Cys³³)
CAS Number: 203460-30-4

R. Newcomb, B. Szoke, A. Palma, G. Wang, X.-h. Chen, W. Hopkins, R. Cong, J. Miller, L. Urge, K. Tarczy-Hornoch, J.A. Loo, D.J. Dooley, L. Nadasdi, R.W. Tsien, J. Lemos, and G. Miljanich, Biochemistry, 37, 15353 (1998). (Original)
L. Ürge, B. Szöke, D. Silva, P. Tran-Tau, D. Hom, K. Tarczy-Hornoch, and L. Nádasdi, , Peptides 1998, Proceedings of 25<sup>th</sup> European Peptide Symposium (S. Bajusz and F. Hudecz, eds.), Akadémiai Kiadó Butapest, 748-749 (1998). (S-S Bond)
A. Tottene, S. Volsen, and D. Pietrobon, J. Neurosci., 20, 171 (2000). (Pharmacol.)
G. Wang, G. Dayanithi, R. Newcomb, and J.R. Lemos, J. Neurosci., 19, 9235 (1999). (Pharmacol.)
D. Sochivko, A. Pereverzev, N. Smyth, C. Gissel, T. Schneider, and H. Beck, J. Physiol., 542, 699 (2002). (Pharmacol.)
X. Jing, et al., J. Clin. Invest., 115, 146 (2005). (Pharmacol.)

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