Kurtoxin (0.1mg vial)

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产品名称: Kurtoxin (0.1mg vial)

产品型号: PKT-4375-s

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Kurtoxin (0.1mg vial) 的详细介绍

Product Code: PKT-4375-s
Synonyms/Product Alternate Names: Lys-Ile-Asp-Gly-Tyr-Pro-Val-Asp-Tyr-Trp-Asn-Cys-Lys-Arg-Ile-Cys-Trp-Tyr-Asn-Asn-Lys-Tyr-Cys-Asn-Asp-Leu-Cys-Lys-Gly-Leu-Lys-Ala-Asp-Ser-Gly-Tyr-Cys-Trp-Gly-Trp-Thr-Leu-Ser-Cys-Tyr-Cys-Gln-Gly-Leu-Pro-Asp-Asn-Ala-Arg-Ile-Lys-Arg-Ser-Gly-Arg-Cys-Arg-Ala

T-type Ca2+ Channel Blocker
Origin: (Scorpion, Parabuthus transvaalicus)
Storage Conditions: -20 °C
Molecular Weight: 7386.4
Molecular Formula: C₃₂₄H₄₇₈N₉₄O₉₀S₈
Disulfide Bonds: (Disulfide bonds between Cys¹²-Cys⁶¹Cys¹⁶-Cys³⁷, Cys²³-Cys⁴⁴, and Cys²⁷-Cys⁴⁶)

R.S-I. Chuang, H. Jaffe, L. Cribbs, E. Perez-Reyes, and K.J. Swartz, Nat. Neurosci., 1, 668 (1998). (Original)
S.S. Sidach and I.M. Mintz, J. Neurosci., 22, 2023 (2002). (Pharmacol.; Specificity for Ca<sup>2+</sup> Channel Blocking Activity)
T. Olamendi-Portugal, B.I. Garcá, I. López-González, J. Van Der Walt, K. Dyason, C. Ulens, J. Tytgat, R. Felix, A. Darszon, and L.D. Possani, Biochem. Biophys. Res. Commun., 299, 562 (2002). (Pharmacol.)
I. López-González, T. Olamendi-Portugal, J.L. De La Vega-Beltrán, J. Van der Walt, K. Dyason, L.D. Possani, R. Felix, and A. Darszon, Biochem. Biophys. Res. Commun., 300, 408 (2003). (Pharmacol.)
H. Nishio, Y. Nishiuchi, M. Ishimaru, and T. Kimura, Lett. Pept. Sci., in press. (Chem. Synthesis & S-S Bond)

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