Lungkine is a CXC chemokine that is expressed in lung epithelial cells and, to a lesser extent, in certain fetal tissues. No human homolog has been identified, and a specific cell surface receptor has not yet been found. Lungkine expression in lung tissue is elevated in response to inflammation, at which time it acts to specifically recruit neutrophils and direct them into the lung airway. Recombinant Murine Lungkine is a 16.3 kDa CXC chemokine consisting of 142 amino acid residues, including four conserved cysteine residues present in CXC chemokines.
Source: E.coli
Synonyms: None
AA Sequence: QELRCLCIQE HSEFIPLKLI KNIMVIFETI YCNRKEVIAV PKNGSMICLD PDAPWVKATV GPITNRFLPE DLKQKEFPPA MKLLYSVEHE KPLYLSFGRP ENKRIFPFPI RETSRHFADL AHNSDRNFLR DSSEVSLTGS DA
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
Biological Activity: Determined by its ability to chemoattract human neutrophils using a concentration range of 20.0-100.0 ng/ml.
Note:
20μg is the largest vial size for this product. Larger sizes supplied as multiple 5μg and/or 20μg vials.
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