FGF-21 is a secreted growth factor that is a member of the FGF family. Proteins of this family play a central role during prenatal development, postnatal growth and regeneration of a variety of tissues, by promoting cellular proliferation and differentiation. FGF-21, in the presence of β-Klotho as a protein cofactor, signals through the FGFR 1c and 4 receptors, and stimulates insulin-independent glucose uptake by adipocytes. Recombinant Human FGF-21 is a 19.5 kDa protein containing 182 amino acid residues.
Source: E.coli
Synonyms: Fibroblast Growth Factor-21, FGFL
AA Sequence: MHPIPDSSPL LQFGGQVRQR YLYTDDAQQT EAHLEIREDG TVGGAADQSP ESLLQLKALK PGVIQILGVK TSRFLCQRPD GALYGSLHFD PEACSFRELL LEDGYNVYQS EAHGLPLHLP GNKSPHRDPA PRGPARFLPL PGLPPALPEP PGILAPQPPD VGSSDPLSMV GPSQGRSPSY AS
Purity: ≥ 90% by SDS-PAGE gel and HPLC analyses.
Biological Activity: FGF-21, in the absence of β-Klotho, shows weak activity of thymidine uptake by BaF3 cells expressing FGF receptors.
本公司网站所展示销售的产品仅供科研！
沪公网安备 31011202007337号
