Exodus-2 is a CC chemokine that signals through the CCR7 receptor. It is expressed in lymph nodes of certain endothelial cells, and in the spleen and appendix. Exodus-2 chemoattracts T and B lymphocytes and inhibits hematopoiesis. Exodus-2 contains six cysteine residues, including the four conserved cysteines present in CC chemokines. Recombinant Human Exodus-2 is a 12.2 kDa protein containing 111 amino acid residues.
Source: E.coli
Synonyms: CCL21, 6Ckine, SLC
AA Sequence: SDGGAQDCCL KYSQRKIPAK VVRSYRKQEP SLGCSIPAIL FLPRKRSQAE LCADPKELWV QQLMQHLDKT PSPQKPAQGC RKDRGASKTG KKGKGSKGCR KTERSQTPKG P
Biological Activity: Determined by its ability to chemoattract total lymphocyte population using a concentration range of 10.0-100.0 ng/ml.
Purity: ≥ 98% by SDS-PAGE gel and HPLC analyses.
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