Monoclonal Antibody

human

Recombinant Serum amyloid A-1 Protein

mouse

Human

specific for Human SAA1 denatured and native forms

ELISA

Serum amyloid A protein, also named SAA, Amyloid protein A, Amyloid fibril protein AA, SAA1, SAA2 and PIG4, is an acute phase apolipoprotein reactant which is produced mostly by hepatocytes and under regulation of inflammatory cytokines. SAA1 is produced mainly in the liver and circulates in low levels in the blood. SAA1 may play a role in the immune system and facilitate the repair of injured tissues, it also acts as an antibacterial agent, and signals the migration of germ-fighting cells to sites of infection. SAA1 also functions as an apolipoprotein of the HDL complex. The SAA1 cleavage product a designated amyloid protein A is deposited systemically as amyloid in vital organs such as the liver, spleen, and kidneys in chronic inflammatory diseases patients. These deposits are extremely insoluble and resistant to proteolysis; they disrupt tissue structure and compromise performance.

monoclonal

IgG2b

>95%,Protein G purified

Non-conjugated

Preservative: 15mmol/L NaN3 Constituents: 0.1mol/L Nacl

liquid

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

SAA1, Serum amyloid A-1 protein, Amyloid fibril protein AA

3657761