Monoclonal Antibody

human

Recombinant Human RRM1 Protein

mouse

Human

specific for human RRM1 denatured and native forms.

ELISA,IHC;Recommended dilution:IHC:1:50-1:500

This gene encodes one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an
enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in S phase of dividing cells.It is one of several genes located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor,rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. This gene may play a role in malignancies and disease that involve this region.

monoclonal

>95%,protein G purifed

Non-conjugated

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

liquid

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Ribonucleotide Reductase M1 RRM1 RR1

0205181