Monoclonal Antibody

human

Recombinant Human MSH6 Protein

mouse

Human

specific for human Msh6 denatured and native forms.

ELISA,IHC;Recommended dilution:IHC:1:50-1:500

This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the
recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa,called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein
heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular
switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be
associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts
variants encoding different isoforms have beendescribed.

monoclonal

>95%,protein G purifed

Non-conjugated

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

liquid

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

MutS Homolog 6 GTBP HSAP2 DNA Mismatch Repair Protein Msh6 G/T Mismatch-Binding Protein

0150321