Monoclonal Antibody

human

Recombinant Human S100B protein

mouse

Human

specific for S100B denatured forms

ELISA

Weakly binds calcium but binds zinc very tightly-distinct s with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-s. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.

monoclonal

IgG1

>95%,protein G purifed

Non-conjugated

Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

liquid

Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

S100B ,S-100 protein beta chain,S-100 protein subunit beta,S100 calcium-binding protein B

106771