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Antibodies
Anti-FBP2 Antibody
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产品名称:
Anti-FBP2 Antibody
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简单介绍
Anti-FBP2
Antibody
Anti-FBP2 Antibody
的详细介绍
Overview
Name:
Anti-FBP2
Antibody
See all FBP2 primary antibodies
Description:
Rabbit polyclonal antibody to FBP2
Specificity:
The antibody detects endogenous levels of total FBP2 protein.
Applications:
IHC
Reactivity:
Human
Immunogen:
Full length fusion protein
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Antigen affinity purification.
Concentration:
2mg / ml
Formulation:
Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage:
Store at -20?C
Target
Function:
Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Tissue Specificity:
Expressed in skeletal muscle (at protein level).
Sequence Similarities:
Belongs to the FBPase class 1 family.
Cellular Location:
Cell junction. Cytoplasm. Nucleus. Cytoplasm > Myofibril > Sarcomere > Z line.
In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
Database Links:
Entrez Gene: 8789?Human
Omim: 603027?Human
SwissProt: O00757?Human
Unigene: 61255?Human
Synonyms:
6-bisphosphatase isozyme 2 Antibody
6-bisphosphate 1-phosphohydrolase 2 Antibody
D fructose 1 6 bisphosphate 1 phosphohydrolase 2 Antibody
D-fructose-1 Antibody
F16P2_HUMAN Antibody
FBP 2 Antibody
FBP2 Antibody
FBPase Antibody
FBPase 2 Antibody
fructose 1 6 bisphosphatase 2 Antibody
Fructose 1 6 bisphosphatase isozyme 2 Antibody
Fructose-1 Antibody
Hexosediphosphatase Antibody
MGC142192 Antibody
Muscle FBPase Antibody
Muscle fructose bisphosphatase Antibody
Information:
Target information shown above is from the UniProt Consortium.
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