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Anti-FBP2 Antibody

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产品名称: Anti-FBP2 Antibody
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简单介绍

Anti-FBP2 Antibody


Anti-FBP2 Antibody  的详细介绍
Name: Anti-FBP2 Antibody
See all FBP2 primary antibodies
Description: Rabbit polyclonal antibody to FBP2
Specificity: The antibody detects endogenous levels of total FBP2 protein.
Applications: IHC
Reactivity: Human
Immunogen: Full length fusion protein
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Catalyzes the hydrolysis of fructose 1,6-bisphosphate to fructose 6-phosphate in the presence of divalent cations and probably participates in glycogen synthesis from carbohydrate precursors, such as lactate.
Tissue Specificity: Expressed in skeletal muscle (at protein level).
Sequence Similarities: Belongs to the FBPase class 1 family.
Cellular Location: Cell junction. Cytoplasm. Nucleus. Cytoplasm > Myofibril > Sarcomere > Z line.

In neonatal cardiomyocytes, distributed throughout the cytosol, accumulating in the intercalated disks which occur at the Z line of cardiomyocytes and connect adjacent cells, and also located in the nucleus; dissociates from the Z line following an increase in cytosolic Ca(2+) concentration (By similarity). In muscle precursor cells, localizes predominantly to the nucleus and to a lesser extent to the cytoplasm at the proliferative phase, while mainly localizing to the cytoplasm at the differentiation phase (By similarity). Colocalizes with ALDOA and alpha-actinin on both sides of the Z line of skeletal muscle; dissociates rapidly from the Z line following an increase in cytosolic Ca(2+) concentration.
Database Links:
  • Entrez Gene: 8789?Human
  • Omim: 603027?Human
  • SwissProt: O00757?Human
  • Unigene: 61255?Human
  • Synonyms:
  • 6-bisphosphatase isozyme 2 Antibody
  • 6-bisphosphate 1-phosphohydrolase 2 Antibody
  • D fructose 1 6 bisphosphate 1 phosphohydrolase 2 Antibody
  • D-fructose-1 Antibody
  • F16P2_HUMAN Antibody
  • FBP 2 Antibody
  • FBP2 Antibody
  • FBPase Antibody
  • FBPase 2 Antibody
  • fructose 1 6 bisphosphatase 2 Antibody
  • Fructose 1 6 bisphosphatase isozyme 2 Antibody
  • Fructose-1 Antibody
  • Hexosediphosphatase Antibody
  • MGC142192 Antibody
  • Muscle FBPase Antibody
  • Muscle fructose bisphosphatase Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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