产品资料

Anti-FANCL Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-FANCL Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-FANCL Antibody


Anti-FANCL Antibody  的详细介绍
Name: Anti-FANCL Antibody
See all FANCL primary antibodies
Description: Goat polyclonal antibody to FANCL.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human FANCL (internal region).
Sequence: C-QNLKDVLEIDFP
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Ubiquitin ligase protein that mediates monoubiquitination of FANCD2, a key step in the DNA damage pathway. Also mediates monoubiquitination of FANCI. May stimulate the ubiquitin release from UBE2W. May be required for proper primordial germ cell proliferation in the embryonic stage, whereas it is probably not needed for spermatogonial proliferation after birth.
Involvement in Disease: Fanconi anemia complementation group L: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Post-Translational Modification: The RING-type zinc finger domain is monoubiquitinated in the presence of UBE2T and UBE2W.
Cellular Location: Cytoplasm. Nucleus.
Database Links:
  • Entrez Gene: 55120 Human
  • Omim: 608111 Human
  • SwissProt: Q9NW38 Human
  • Unigene: 631890 Human
    		•
    Synonyms:
  • E3 ubiquitin-protein ligase FANCL Antibody
  • FAAP43 Antibody
  • FANCL Antibody
  • FANCL_HUMAN Antibody
  • Fanconi anemia complementation group L Antibody
  • Fanconi anemia group L protein Antibody
  • Fanconi anemia-associated polypeptide of 43 kDa Antibody
  • FLJ10335 Antibody
  • PHD finger protein 9 Antibody
  • PHF9 Antibody
  • POG Antibody
  • Ubiquitin ligase protein FANCL Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号