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Anti-FANCG Antibody

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产品名称: Anti-FANCG Antibody
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简单介绍

Anti-FANCG Antibody


Anti-FANCG Antibody  的详细介绍
Name: Anti-FANCG Antibody
See all FANCG primary antibodies
Description: Rabbit polyclonal antibody to FANCG
Specificity: The antibody detects endogenous levels of total FANCG protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human Fanconi anemia, complementation group G
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.3mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
Tissue Specificity: Highly expressed in testis and thymus. Found in lymphoblasts.
Involvement in Disease: Fanconi anemia complementation group G: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Cellular Location: Nucleus. Cytoplasm.

The major form is nuclear. The minor form is cytoplasmic.
Database Links:
  • Entrez Gene: 2189?Human
  • Omim: 602956?Human
  • SwissProt: O15287?Human
  • Unigene: 591084?Human
  • Synonyms:
  • DNA repair protein XRCC9 Antibody
  • FAG Antibody
  • FANCG Antibody
  • FANCG_HUMAN Antibody
  • Fanconi anaemia complementation group G Antibody
  • Fanconi anemia group G protein Antibody
  • Protein FACG Antibody
  • X ray repair, complementing defective, in Chinese hamster cells 9 Antibody
  • X-ray repair, complementing defective, in Chinese hamster, 9 Antibody
  • XRCC9 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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