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Anti-FANCG (Phospho-Ser383) Antibody

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产品名称: Anti-FANCG (Phospho-Ser383) Antibody
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Anti-FANCG (Phospho-Ser383) Antibody


Anti-FANCG (Phospho-Ser383) Antibody  的详细介绍
Name: Anti-FANCG (Phospho-Ser383) Antibody
See all FANCG primary antibodies
Description: Rabbit polyclonal antibody to FANCG (Phospho-Ser383)
Specificity: The antibody detects endogenous levels of FANCG only when phosphorylated at serine 383.
Applications: WB
Dilutions: Western blotting: 1:500~1:3000
Reactivity: Human
Immunogen: Peptide sequence around phosphorylation site of serine 383 (R-F-S(p)-P-P) derived from Human FANCG.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration: 1.0mg / ml
Formulation: Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage: Store at -20˚C
Function: DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be implicated in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. Candidate tumor suppressor gene.
Tissue Specificity: Highly expressed in testis and thymus. Found in lymphoblasts.
Involvement in Disease: Fanconi anemia complementation group G: A disorder affecting all bone marrow elements and resulting in anemia, leukopenia and thrombopenia. It is associated with cardiac, renal and limb malformations, dermal pigmentary changes, and a predisposition to the development of malignancies. At the cellular level it is associated with hypersensitivity to DNA-damaging agents, chromosomal instability (increased chromosome breakage) and defective DNA repair.
Cellular Location: Nucleus. Cytoplasm.

The major form is nuclear. The minor form is cytoplasmic.
Database Links:
  • Entrez Gene: 2189 Human
  • Omim: 602956 Human
  • SwissProt: O15287 Human
  • Unigene: 591084 Human
    		•
    Synonyms:
  • DNA repair protein XRCC9 Antibody
  • FAG Antibody
  • FANCG Antibody
  • FANCG_HUMAN Antibody
  • Fanconi anaemia complementation group G Antibody
  • Fanconi anemia group G protein Antibody
  • Protein FACG Antibody
  • X ray repair, complementing defective, in Chinese hamster cells 9 Antibody
  • X-ray repair, complementing defective, in Chinese hamster, 9 Antibody
  • XRCC9 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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