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Anti-FADS1 Antibody

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产品名称: Anti-FADS1 Antibody
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简单介绍

Anti-FADS1 Antibody


Anti-FADS1 Antibody  的详细介绍
Name: Anti-FADS1 Antibody
See all FADS1 primary antibodies
Description: Rabbit polyclonal antibody to FADS1
Specificity: The antibody detects endogenous levels of total FADS1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human fatty acid desaturase 1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.8mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Isoform 2 does not exhibit any catalytic activity toward 20:3n-6, but it may enhance FADS2 activity (By similarity). Isoform 1 is a component of a lipid metabolic pathway that catalyzes biosynthesis of highly unsaturated fatty acids (HUFA) from precursor essential polyunsaturated fatty acids (PUFA) linoleic acid (LA) (18:2n-6) and alpha-linolenic acid (ALA) (18:3n-3). Catalyzes the desaturation of dihomo-gamma-linoleic acid (DHGLA) (20:3n-6) and eicosatetraenoic acid (20:4n-3) to generate arachidonic acid (AA) (20:4n-6) and eicosapentaenoic acid (EPA)(20:5n-3), respectively.
Tissue Specificity: Widely expressed, with highest levels in liver, brain, adrenal gland and heart. Highly expressed in fetal liver and brain.
Sequence Similarities: Belongs to the fatty acid desaturase type 1 family.
Cellular Location: Endoplasmic reticulum membrane. Mitochondrion.
Database Links:
  • Entrez Gene: 3992?Human
  • Omim: 606148?Human
  • SwissProt: O60427?Human
  • Unigene: 503546?Human
    		•
    Synonyms:
  • D5D Antibody
  • Delta 5 desaturase Antibody
  • Delta 5 fatty acid desaturase Antibody
  • Delta(5) desaturase Antibody
  • Delta(5) fatty acid desaturase Antibody
  • Delta-5 desaturase Antibody
  • FADS1 Antibody
  • FADS1_HUMAN Antibody
  • FADS6 Antibody
  • FADSD5 Antibody
  • Fatty acid desaturase 1 Antibody
  • FLJ38956 Antibody
  • Linoleoyl CoA desaturase (delta 6 desaturase) like 1 Antibody
  • LLCDL1 Antibody
  • TU12 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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