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Anti-Factor XIIIa Antibody

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产品名称: Anti-Factor XIIIa Antibody
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Anti-Factor XIIIa Antibody


Anti-Factor XIIIa Antibody  的详细介绍
Name: Anti-Factor XIIIa Antibody
See all Factor XIIIa primary antibodies
Description: Rabbit polyclonal antibody to Factor XIIIa
Applications: WB, IF
Dilutions: Western blotting: 1:500-1:3000 Immunofluorescence: 1:100-1:200
Reactivity: Human
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 245 and 494 of Human F13A1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Predicted MW: 83kd
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Function: Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Involvement in Disease: Factor XIII subunit A deficiency: An autosomal recessive hematologic disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
Sequence Similarities: Belongs to the transglutaminase superfamily. Transglutaminase family.
Post-Translational Modification: The activation peptide is released by thrombin.
Cellular Location: Cytoplasm. Secreted.

Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
Database Links:
  • Entrez Gene: 2162 Human
  • Omim: 134570 Human
  • SwissProt: P00488 Human
  • Unigene: 335513 Human
    		•
    Synonyms:
  • bA525O21.1 (coagulation factor XIII, A1 polypeptide) Antibody
  • Coagulation factor XIII A chain Antibody
  • Coagulation factor XIII A1 polypeptide Antibody
  • Coagulation factor XIII A1 subunit Antibody
  • Coagulation factor XIII, A polypeptide Antibody
  • Coagulation factor XIIIa Antibody
  • F13A Antibody
  • F13a1 Antibody
  • F13A_HUMAN Antibody
  • Factor XIIIa Antibody
  • Fibrin stabilizing factor, A subunit Antibody
  • Fibrinoligase Antibody
  • FSF, A subunit Antibody
  • Protein glutamine gamma glutamyltransferase A chain Antibody
  • Protein-glutamine gamma-glutamyltransferase A chain Antibody
  • TGase Antibody
  • Transglutaminase A chain Antibody
  • Transglutaminase, plasma Antibody
  • Transglutaminase. plasma Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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