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Anti-Factor X Antibody

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产品名称: Anti-Factor X Antibody
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简单介绍

Anti-Factor X Antibody


Anti-Factor X Antibody  的详细介绍
Name: Anti-Factor X Antibody
See all Factor X primary antibodies
Description: Mouse monoclonal (F10-1) antibody to Factor X.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Human Factor X.
Host: Mouse
Clonality: Monoclonal
Clone: F10-1
Myeloma: Sp2/0-Ag14
Isotype: IgG1
Conjugate: Unconjugated
Concentration: Reconstitution dependent.
Purity: Protein G affinity chromatagraphy.
Product Form: Lyophilised
Reconstitution: Reconstitute with double distilled water.
Formulation: Lyophilised from a solution of 0.01M Phosphate Buffered Saline, pH 7.2.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Factor Xa is a vitamin K-dependent glycoprotein that converts prothrombin to thrombin in the presence of factor Va, calcium and phospholipid during blood clotting.
Tissue Specificity: Plasma; synthesized in the liver.
Involvement in Disease: Factor X deficiency: A hemorrhagic disease with variable presentation. Affected individuals can manifest prolonged nasal and mucosal hemorrhage, menorrhagia, hematuria, and occasionally hemarthrosis. Some patients do not have clinical bleeding diathesis.
Sequence Similarities: Belongs to the peptidase S1 family.
Post-Translational Modification: The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 2159 Human
  • Omim: 227600 Human
  • SwissProt: P00742 Human
  • Unigene: 361463 Human
    		•
    Synonyms:
  • Activated factor Xa heavy chain Antibody
  • Coagulation factor X Antibody
  • F10 Antibody
  • FA10_HUMAN Antibody
  • Factor X Antibody
  • factor Xa Antibody
  • FX Antibody
  • FXA Antibody
  • Prothrombinase Antibody
  • Stuart factor Antibody
  • Stuart Prower factor Antibody
  • Stuart-Prower factor Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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