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Antibodies
Anti-Factor VII Antibody
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产品名称:
Anti-Factor VII Antibody
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简单介绍
Anti-Factor VII
Antibody
Anti-Factor VII Antibody
的详细介绍
Overview
Name:
Anti-Factor VII
Antibody
See all Factor VII primary antibodies
Description:
Rabbit polyclonal antibody to Factor VII
Applications:
WB, IHC
Reactivity:
Human, Mouse
Immunogen:
Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
Purified by antigen-affinity chromatography.
Formulation:
Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage:
Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.
Target
Function:
Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).
Tissue Specificity:
Plasma and liver.
Sequence Similarities:
Belongs to the peptidase S1 family.
Post-Translational Modification:
The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
Cellular Location:
Secreted.
Database Links:
Entrez Gene: 2155?Human
Entrez Gene: 14068?Mouse
Omim: 227500?Human
Omim: 613878?Human
SwissProt: P08709?Human
SwissProt: P70375?Mouse
Unigene: 36989?Human
Unigene: 4827?Mouse
Synonyms:
Cf7 Antibody
Coagulation factor VII Antibody
coagulation factor VII (serum prothrombin conversion accelerator) Antibody
Eptacog alfa Antibody
F7 Antibody
F7 deficiency Antibody
FA7_HUMAN Antibody
Factor VII Antibody
Factor VII deficiency Antibody
Factor VII heavy chain Antibody
Factor VII light chain Antibody
FVII Antibody
FVII coagulation protein Antibody
Hypoproconvertinemia Antibody
OTTHUMP00000018733 Antibody
OTTHUMP00000018734 Antibody
Proconvertin Antibody
Serum prothrombin conversion accelerator Antibody
SPCA Antibody
Information:
Target information shown above is from the UniProt Consortium.
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