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Anti-Factor VII Antibody

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产品名称: Anti-Factor VII Antibody
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简单介绍

Anti-Factor VII Antibody


Anti-Factor VII Antibody  的详细介绍
Name: Anti-Factor VII Antibody
See all Factor VII primary antibodies
Description: Rabbit polyclonal antibody to Factor VII
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 209 and 444 of Factor VII
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.
Function: Initiates the extrinsic pathway of blood coagulation. Serine protease that circulates in the blood in a zymogen form. Factor VII is converted to factor VIIa by factor Xa, factor XIIa, factor IXa, or thrombin by minor proteolysis. In the presence of tissue factor and calcium ions, factor VIIa then converts factor X to factor Xa by limited proteolysis. Factor VIIa will also convert factor IX to factor IXa in the presence of tissue factor and calcium (By similarity).
Tissue Specificity: Plasma and liver.
Sequence Similarities: Belongs to the peptidase S1 family.
Post-Translational Modification: The vitamin K-dependent, enzymatic carboxylation of some glutamate residues allows the modified protein to bind calcium.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 2155?Human
  • Entrez Gene: 14068?Mouse
  • Omim: 227500?Human
  • Omim: 613878?Human
  • SwissProt: P08709?Human
  • SwissProt: P70375?Mouse
  • Unigene: 36989?Human
  • Unigene: 4827?Mouse
  • Synonyms:
  • Cf7 Antibody
  • Coagulation factor VII Antibody
  • coagulation factor VII (serum prothrombin conversion accelerator) Antibody
  • Eptacog alfa Antibody
  • F7 Antibody
  • F7 deficiency Antibody
  • FA7_HUMAN Antibody
  • Factor VII Antibody
  • Factor VII deficiency Antibody
  • Factor VII heavy chain Antibody
  • Factor VII light chain Antibody
  • FVII Antibody
  • FVII coagulation protein Antibody
  • Hypoproconvertinemia Antibody
  • OTTHUMP00000018733 Antibody
  • OTTHUMP00000018734 Antibody
  • Proconvertin Antibody
  • Serum prothrombin conversion accelerator Antibody
  • SPCA Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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