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Anti-F13A1 Antibody

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产品名称: Anti-F13A1 Antibody
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Anti-F13A1 Antibody


Anti-F13A1 Antibody  的详细介绍
Name: Anti-F13A1 Antibody
See all F13A1 primary antibodies
Description: Rabbit polyclonal antibody to F13A1
Specificity: The antibody detects endogenous levels of total F13A1 protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human Coagulation factor XIII, A1 polypeptide
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 0.5mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Factor XIII is activated by thrombin and calcium ion to a transglutaminase that catalyzes the formation of gamma-glutamyl-epsilon-lysine cross-links between fibrin chains, thus stabilizing the fibrin clot. Also cross-link alpha-2-plasmin inhibitor, or fibronectin, to the alpha chains of fibrin.
Involvement in Disease: Factor XIII subunit A deficiency: An autosomal recessive hematologic disorder characterized by a life-long bleeding tendency, impaired wound healing and spontaneous abortion in affected women.
Sequence Similarities: Belongs to the transglutaminase superfamily. Transglutaminase family.
Post-Translational Modification: The activation peptide is released by thrombin.
Cellular Location: Cytoplasm. Secreted.

Secreted into the blood plasma. Cytoplasmic in most tissues, but also secreted in the blood plasma.
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