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Anti-F11R Antibody

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产品名称: Anti-F11R Antibody
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简单介绍

Anti-F11R Antibody


Anti-F11R Antibody  的详细介绍
Name: Anti-F11R Antibody
See all F11R primary antibodies
Description: Goat polyclonal antibody to F11R.
Applications: ELISA, WB
Reactivity: Human
Immunogen: Synthetic peptide corresponding to Human F11R (C terminal).
Sequence: C-QPSARSEGEFKQTS
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 µg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3 (PubMed:11489913). The association of the PARD6-PARD3 complex may prevent the interaction of PARD3 with JAM1, thereby preventing tight junction assembly (By similarity). Plays a role in regulating monocyte transmigration involved in integrity of epithelial barrier (By similarity). Ligand for integrin alpha-L/beta-2 involved in memory T-cell and neutrophil transmigration (PubMed:11812992). Involved in platelet activation (PubMed:10753840).
Tissue Specificity: Expressed in endothelium, epithelium and leukocytes (at protein level).
Sequence Similarities: Belongs to the immunoglobulin superfamily.
Post-Translational Modification: N-glycosylated.
Cellular Location: Cell junction > Tight junction. Cell membrane.

Localized at tight junctions of both epithelial and endothelial cells.
Database Links:
  • Entrez Gene: 50848 Human
  • Omim: 605721 Human
  • SwissProt: Q9Y624 Human
  • Unigene: 517293 Human
    		•
    Synonyms:
  • CD 321 Antibody
  • CD321 Antibody
  • CD321 antigen Antibody
  • ESTM33 Antibody
  • F11 receptor Antibody
  • F11R Antibody
  • JAM Antibody
  • JAM 1 Antibody
  • JAM A Antibody
  • JAM-1 Antibody
  • JAM-A Antibody
  • JAM1 Antibody
  • JAM1_HUMAN Antibody
  • JAMA Antibody
  • JCAM Antibody
  • Jcam1 Antibody
  • Junction adhesion molecule 1 Antibody
  • Junction adhesion molecule, mouse, homolog of Antibody
  • Junctional Adhesion Molecule 1 Antibody
  • Junctional adhesion molecule A Antibody
  • KAT Antibody
  • Ly106 Antibody
  • PAM 1 Antibody
  • PAM-1 Antibody
  • PAM1 Antibody
  • Platelet adhesion molecule Antibody
  • Platelet adhesion molecule 1 Antibody
  • Platelet F11 receptor Antibody
  • PRO301 Antibody
  • UNQ264 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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