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Anti-F-box only protein 2 Antibody

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产品名称: Anti-F-box only protein 2 Antibody
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Anti-F-box only protein 2 Antibody


Anti-F-box only protein 2 Antibody  的详细介绍
Name: Anti-F-box only protein 2 Antibody
See all F-box only protein 2 primary antibodies
Description: Rabbit polyclonal antibody to F-box only protein 2
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 234 and 296 of F-box only protein 2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 1XPBS, 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20?C for long term preservation (recommended). Store at 4?C for short term use.
Function: Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. Involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins by recognizing and binding sugar chains on unfolded glycoproteins that are retrotranslocated into the cytosol and promoting their ubiquitination and subsequent degradation. Prevents formation of cytosolic aggregates of unfolded glycoproteins that have been retrotranslocated into the cytosol. Able to recognize and bind denatured glycoproteins, preferentially those of the high-mannose type (By similarity).
Cellular Location: Cytoplasm. Microsome membrane.
Database Links:
  • Entrez Gene: 26232?Human
  • Omim: 607112?Human
  • SwissProt: Q9UK22?Human
  • Unigene: 132753?Human
  • Unigene: 556006?Human
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    Synonyms:
  • F box gene 1 Antibody
  • F box only protein 2 Antibody
  • F box protein 2 Antibody
  • F box protein only 2 Antibody
  • F-box only protein 2 Antibody
  • FBG 1 Antibody
  • FBG1 Antibody
  • Fbs 1 Antibody
  • Fbs1 Antibody
  • Fbs2 Antibody
  • FBX 2 Antibody
  • FBX2 Antibody
  • FBX2_HUMAN Antibody
  • FBXO 2 Antibody
  • FBXO2 Antibody
  • Neural F box protein NFB42 Antibody
  • Neural F-box protein, 42-KD, rat, homolog of Antibody
  • NFB 42 Antibody
  • NFB42 Antibody
  • OCP1 Antibody
  • organ of Corti protein 1 Antibody
  • Prpl4 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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