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Anti-ETV1 Antibody

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产品名称: Anti-ETV1 Antibody
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简单介绍

Anti-ETV1 Antibody


Anti-ETV1 Antibody  的详细介绍
Name: Anti-ETV1 Antibody
See all ETV1 primary antibodies
Description: Rabbit polyclonal antibody to ETV1.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity: Human, Mouse, Rat
Immunogen: Recombinant protein of human ETV1.
Protein Length: 477
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Tissue Specificity: Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Involvement in Disease: Ewing sarcoma: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors.
Sequence Similarities: Belongs to the ETS family.
Post-Translational Modification: Sumoylated.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 2115?Human
  • Entrez Gene: 14009?Mouse
  • Entrez Gene: 362733?Rat
  • Omim: 600541?Human
  • SwissProt: P50549?Human
  • SwissProt: P41164?Mouse
  • Unigene: 22634?Human
  • Unigene: 4866?Mouse
  • Unigene: 56219?Rat
  • Synonyms:
  • DKFZp781L0674 Antibody
  • ER81 Antibody
  • ER81 protein Antibody
  • ER81, mouse, homolog of Antibody
  • ETS translocation variant 1 Antibody
  • ets variant gene 1 Antibody
  • Ets-related protein 81 Antibody
  • Etsrp81 Antibody
  • ETV 1 Antibody
  • ETV1 Antibody
  • ETV1_HUMAN Antibody
  • MGC104699 Antibody
  • MGC120533 Antibody
  • MGC120534 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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