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Antibodies
Anti-ETV1 Antibody
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产品名称:
Anti-ETV1 Antibody
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简单介绍
Anti-ETV1
Antibody
Anti-ETV1 Antibody
的详细介绍
Overview
Name:
Anti-ETV1
Antibody
See all ETV1 primary antibodies
Description:
Rabbit polyclonal antibody to ETV1.
Applications:
WB, IHC, IF
Dilutions:
WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:100.
Reactivity:
Human, Mouse, Rat
Immunogen:
Recombinant protein of human ETV1.
Protein Length:
477
Host:
Rabbit
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Unconjugated
Purification:
Affinity purification.
Product Form:
Liquid
Formulation:
Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage:
Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Target
Function:
Transcriptional activator that binds to DNA sequences containing the consensus pentanucleotide 5'-CGGA[AT]-3'.
Tissue Specificity:
Very highly expressed in brain, highly expressed in testis, lung and heart, moderately in spleen, small intestine, pancreas and colon, weakly in liver, prostate and thymus, very weakly in skeletal muscle, kidney and ovary and not in placenta and peripheral blood leukocytes.
Involvement in Disease:
Ewing sarcoma: A highly malignant, metastatic, primitive small round cell tumor of bone and soft tissue that affects children and adolescents. It belongs to the Ewing sarcoma family of tumors, a group of morphologically heterogeneous neoplasms that share the same cytogenetic features. They are considered neural tumors derived from cells of the neural crest. Ewing sarcoma represents the less differentiated form of the tumors.
Sequence Similarities:
Belongs to the ETS family.
Post-Translational Modification:
Sumoylated.
Cellular Location:
Nucleus.
Database Links:
Entrez Gene: 2115?Human
Entrez Gene: 14009?Mouse
Entrez Gene: 362733?Rat
Omim: 600541?Human
SwissProt: P50549?Human
SwissProt: P41164?Mouse
Unigene: 22634?Human
Unigene: 4866?Mouse
Unigene: 56219?Rat
Synonyms:
DKFZp781L0674 Antibody
ER81 Antibody
ER81 protein Antibody
ER81, mouse, homolog of Antibody
ETS translocation variant 1 Antibody
ets variant gene 1 Antibody
Ets-related protein 81 Antibody
Etsrp81 Antibody
ETV 1 Antibody
ETV1 Antibody
ETV1_HUMAN Antibody
MGC104699 Antibody
MGC120533 Antibody
MGC120534 Antibody
Information:
Target information shown above is from the UniProt Consortium.
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