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Anti-ETFB Antibody

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产品名称: Anti-ETFB Antibody
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简单介绍

Anti-ETFB Antibody


Anti-ETFB Antibody  的详细介绍
Name: Anti-ETFB Antibody
See all ETFB primary antibodies
Description: Rabbit polyclonal antibody to ETFB
Specificity: The antibody detects endogenous levels of total ETFB protein.
Applications: WB, IHC
Reactivity: Human
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human electron-transfer-flavoprotein, beta polypeptide
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.9mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: The electron transfer flavoprotein serves as a specific electron acceptor for several dehydrogenases, including five acyl-CoA dehydrogenases, glutaryl-CoA and sarcosine dehydrogenase. It transfers the electrons to the main mitochondrial respiratory chain via ETF-ubiquinone oxidoreductase (ETF dehydrogenase).
Tissue Specificity: Abundant in liver, heart and skeletal muscle. A weak expression is seen in the brain, placenta, lung, kidney and pancreas.
Involvement in Disease: Glutaric aciduria 2B: An autosomal recessively inherited disorder of fatty acid, amino acid, and choline metabolism. It is characterized by multiple acyl-CoA dehydrogenase deficiencies resulting in large excretion not only of glutaric acid, but also of lactic, ethylmalonic, butyric, isobutyric, 2-methyl-butyric, and isovaleric acids.
Sequence Similarities: Belongs to the ETF beta-subunit/FixA family.
Post-Translational Modification: Methylated. Trimethylation at Lys-200 and Lys-203 may negatively regulate the activity in electron transfer from Acyl-CoA dehydrogenases.
Cellular Location: Mitochondrion matrix.
Database Links:
  • Entrez Gene: 2109?Human
  • Omim: 130410?Human
  • SwissProt: P38117?Human
  • Unigene: 348531?Human
    		•
    Synonyms:
  • Beta ETF Antibody
  • Beta-ETF Antibody
  • Electron transfer flavoprotein beta polypeptide Antibody
  • Electron transfer flavoprotein beta subunit Antibody
  • Electron transfer flavoprotein subunit beta Antibody
  • Electron transferring flavoprotein beta polypeptide Antibody
  • ETFB Antibody
  • ETFB_HUMAN Antibody
  • FP585 Antibody
  • MADD Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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