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Anti-EPPIN Antibody

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产品名称: Anti-EPPIN Antibody
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简单介绍

Anti-EPPIN Antibody


Anti-EPPIN Antibody  的详细介绍
Name: Anti-EPPIN Antibody
See all EPPIN primary antibodies
Description: Rabbit polyclonal antibody to EPPIN
Specificity: The antibody detects endogenous levels of total EPPIN protein.
Applications: WB, IHC
Reactivity: Human, Mouse
Immunogen: Synthetic peptide corresponding to a region derived from internal residues of human epididymal peptidase inhibitor
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 2.4mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Serine protease inhibitor that plays an essential role in male reproduction and fertility. Modulates the hydrolysis of SEMG1 by KLK3/PSA (a serine protease), provides antimicrobial protection for spermatozoa in the ejaculate coagulum, and binds SEMG1 thereby inhibiting sperm motility.
Tissue Specificity: In testis, expressed and secreted by Sertoli cells, appearing on the surface of testicular and ejaculate spermatozoa. Expressed in the spermatogonia and the earliest preleptotene spermatocytes. In the epididymis, is expressed and secreted by epithelial cells and covers the surface of epididymal spermatozoa and ciliated epithelial cells (at protein level). Expressed specifically in epididymis and testis. Isoform 2 is expressed only in the epididymis. Weak expression is detected in myoid cells as well as spermatogenic cells.
Cellular Location: Secreted. Cell surface.

Bound to the surface of testicular and on the head and tail of ejaculate spermatozoa.
Database Links:
  • Entrez Gene: 57119?Human
  • Entrez Gene: 75526?Mouse
  • Omim: 609031?Human
  • SwissProt: O95925?Human
  • SwissProt: Q9DA01?Mouse
  • Unigene: 121084?Human
    		•
    Synonyms:
  • Cancer/testis antigen 71 Antibody
  • CT 71 Antibody
  • CT71 Antibody
  • dJ461P17.2 Antibody
  • Epididymal protease inhibitor Antibody
  • Eppin Antibody
  • EPPIN 1 Antibody
  • EPPIN 2 Antibody
  • EPPIN 3 Antibody
  • EPPIN1 Antibody
  • EPPIN2 Antibody
  • EPPIN3 Antibody
  • Protease inhibitor WAP7 Antibody
  • Serine peptidase inhibitor like with Kunitz and WAP domains 1 Antibody
  • Serine peptidase inhibitor like with Kunitz and WAP domains 1 (eppin) Antibody
  • SPINLW 1 Antibody
  • SPINLW1 Antibody
  • WAP 7 Antibody
  • WAP four disulfide core domain 7 Antibody
  • WAP four disulfide core domain protein 7 Antibody
  • WAP7 Antibody
  • WFDC 7 Antibody
  • WFDC7 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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