Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody

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产品名称: Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody

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Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody 的详细介绍

Name:	Anti-Ephrin B1 / B2 / B3 (Phospho-Tyr324) Antibody See all Ephrin B1 primary antibodies
Description:	Rabbit polyclonal antibody to Ephrin B1 / B2 / B3 (Phospho-Tyr324)
Specificity:	The antibody detects endogenous levels of Ephrin B1 / B2 / B3 only when phosphorylated at tyrosine 324.
Applications:	WB, IHC
Dilutions:	Western blotting: 1:500~1:1000Immunohistochemistry: 1:50~1:100
Reactivity:	Human
Immunogen:	Peptide sequence around phosphorylation site of tyrosine 324 (G-D-Y(p)-G-H) derived from Human Ephrin B1 / B2 / B3 .
Host:	Rabbit
Clonality:	Polyclonal
Conjugate:	Unconjugated
Purification:	Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy using non-phosphopeptide.
Concentration:	1.0mg / ml
Formulation:	Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Storage:	Store at -20?C / 1 year

Function:	Binds to the receptor tyrosine kinases EPHB1 and EPHA1. Binds to, and induce the collapse of, commissural axons/growth cones in vitro. May play a role in constraining the orientation of longitudinally projecting axons (By similarity).
Tissue Specificity:	Heart, placenta, lung, liver, skeletal muscle, kidney, pancreas.
Involvement in Disease:	Craniofrontonasal syndrome: X-linked inherited syndrome characterized by hypertelorism, coronal synostosis with brachycephaly, downslanting palpebral fissures, clefting of the nasal tip, joint anomalies, longitudinally grooved fingernails and other digital anomalies.
Sequence Similarities:	Belongs to the ephrin family.
Post-Translational Modification:	Inducible phosphorylation of tyrosine residues in the cytoplasmic domain.
Cellular Location:	Membrane.
Database Links:	Entrez Gene: 1947?Human Omim: 300035?Human SwissProt: P98172?Human Unigene: 144700?Human
Synonyms:	CFND Antibody CFNS Antibody Craniofrontonasal syndrome (craniofrontonasal dysplasia) Antibody EFL 3 Antibody EFL-3 Antibody EFL3 Antibody EFNB1 Antibody EFNB1_HUMAN Antibody Elk L Antibody ELK ligand Antibody ELK-L Antibody Eph related receptor tyrosine kinase ligand 2 Antibody EPH-related receptor tyrosine kinase ligand 2 Antibody Ephrin B1 Antibody Ephrin-B1 Antibody EPLG2 Antibody LERK 2 Antibody LERK-2 Antibody LERK2 Antibody Ligand of eph related kinase 2 Antibody MGC8782 Antibody
Information:	Target information shown above is from the UniProt Consortium.

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