产品资料

Anti-EPHA1 Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-EPHA1 Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-EPHA1 Antibody


Anti-EPHA1 Antibody  的详细介绍
Name: Anti-EPHA1 Antibody
See all EPHA1 primary antibodies
Description: Rabbit polyclonal antibody to EPHA1.
Applications: WB, IHC, IF
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:200, IF: 1:50 - 1:200.
Reactivity: Human
Immunogen: Recombinant protein of human EPHA1.
Protein Length: 976
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Receptor tyrosine kinase which binds promiscuously membrane-bound ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling. Binds with a low affinity EFNA3 and EFNA4 and with a high affinity to EFNA1 which most probably constitutes its cognate/functional ligand. Upon activation by EFNA1 induces cell attachment to the extracellular matrix inhibiting cell spreading and motility through regulation of ILK and downstream RHOA and RAC. Plays also a role in angiogenesis and regulates cell proliferation. May play a role in apoptosis.
Tissue Specificity: Overexpressed in several carcinomas.
Sequence Similarities: Belongs to the protein kinase superfamily. Tyr protein kinase family. Ephrin receptor subfamily.
Post-Translational Modification: Phosphorylated. Autophosphorylation is stimulated by its ligand EFNA1.
Cellular Location: Cell membrane.
Database Links:
  • Entrez Gene: 2041?Human
  • Omim: 179610?Human
  • SwissProt: P21709?Human
  • Unigene: 89839?Human
    		•
    Synonyms:
  • EPH Antibody
  • Eph receptor A1 Antibody
  • EPH tyrosine kinase Antibody
  • EPH tyrosine kinase 1 Antibody
  • Epha1 Antibody
  • EPHA1_HUMAN Antibody
  • Ephrin receptor Eph A1 Antibody
  • Ephrin type A receptor 1 Antibody
  • Ephrin type-A receptor 1 Antibody
  • EPHT Antibody
  • EPHT 1 Antibody
  • EPHT1 Antibody
  • Erythropoietin producing hepatoma amplified sequence Antibody
  • Erythropoietin-producing hepatoma receptor Antibody
  • Esk Antibody
  • hEpha1 Antibody
  • MGC163163 Antibody
  • Oncogene EPH Antibody
  • Soluble EPHA1 variant 1 Antibody
  • Soluble EPHA1 variant 2 Antibody
  • Tyrosine protein kinase receptor EPH Antibody
  • Tyrosine-protein kinase receptor EPH Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号