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Anti-Endothelin 1 Antibody

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产品名称: Anti-Endothelin 1 Antibody
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Anti-Endothelin 1 Antibody


Anti-Endothelin 1 Antibody  的详细介绍
Name: Anti-Endothelin 1 Antibody
See all Endothelin 1 primary antibodies
Description: Rabbit polyclonal antibody to Endothelin 1
Applications: WB, IF
Reactivity: Human
Immunogen: Synthetic peptide contain a sequence corresponding to a region within amino acids 141 and 203 of Human EDN1
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 20% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Function: Endothelins are endothelium-derived vasoconstrictor peptides.
Tissue Specificity: Expressed in lung, placental stem villi vessels and in cultured placental vascular smooth muscle cells.
Involvement in Disease: Question mark ears, isolated: An auricular abnormality characterized by a cleft between the lobule and the lower part of the helix, sometimes accompanied by a prominent or deficient upper part of the helix, shallow skin dimple on the posterior surface of the ear, or transposition of the ear lobe/antitragus.

Auriculocondylar syndrome 3: A craniofacial malformation syndrome characterized by variable mandibular anomalies, including mild to severe micrognathia, temporomandibular joint ankylosis, cleft palate, and a characteristic ear malformation that consists of separation of the lobule from the external ear, giving the appearance of a question mark (question-mark ear). Other frequently described features include prominent cheeks, cupped and posteriorly rotated ears, preauricular tags, and microstomia.
Sequence Similarities: Belongs to the endothelin/sarafotoxin family.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 1906 Human
  • Omim: 131240 Human
  • SwissProt: P05305 Human
  • Unigene: 511899 Human
  • Unigene: 713645 Human
    		•
    Synonyms:
  • ARCND3 Antibody
  • Big endothelin-1 Antibody
  • EDN1 Antibody
  • EDN1_HUMAN Antibody
  • Endothelin 1 Antibody
  • ET-1 Antibody
  • ET1 Antibody
  • HDLCQ7 Antibody
  • PPET1 Antibody
  • Preproendothelin 1 Antibody
  • Preproendothelin-1 Antibody
  • QME Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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