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Anti-ENC1 Antibody

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产品名称: Anti-ENC1 Antibody
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简单介绍

Anti-ENC1 Antibody


Anti-ENC1 Antibody  的详细介绍
Name: Anti-ENC1 Antibody
See all ENC1 primary antibodies
Description: Goat polyclonal antibody to ENC1.
Applications: ELISA, WB, IHC
Reactivity: Rat, Human
Immunogen: Synthetic peptide corresponding to Human ENC1 (internal region).
Sequence: TSVSHDKLPKVQC
Host: Goat
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Concentration: 100 μg at 0.5 mg/ml.
Product Form: Liquid
Formulation: Supplied in Tris Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 0.5% BSA.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: Actin-binding protein involved in the regulation of neuronal process formation and in differentiation of neural crest cells. Down-regulates transcription factor NF2L2/NRF2 by decreasing the rate of protein synthesis and not via a ubiquitin-mediated proteasomal degradation mechanism.
Tissue Specificity: Detected in fetal brain tissue, moderate expression in fetal heart, lung and kidney. Highly expressed in ***** brain, particularly high in the hippocampus and amygdala, and spinal chord. Detectable in ***** pancreas. May be down-regulated in neuroblastoma tumors.
Post-Translational Modification: Ubiquitinated by E3 ubiquitin ligase complex formed by CUL3 and RBX1 and probably targeted for proteasome-independent degradation. Quinone-induced oxidative stress increases its ubiquitination.
Cellular Location: Nucleus matrix. Cytoplasm. Cytoplasm > Cytoskeleton.
Database Links:
  • Entrez Gene: 8507?Human
  • Entrez Gene: 294674?Rat
  • Omim: 605173?Human
  • SwissProt: O14682?Human
  • Unigene: 104925?Human
  • Unigene: 3039?Rat
    		•
    Synonyms:
  • CCL 28 Antibody
  • CCL28 Antibody
  • Ectoderm neural cortex protein 1 Antibody
  • Ectoderm-neural cortex protein 1 Antibody
  • Ectodermal neural cortex (with BTB like domain) Antibody
  • ENC 1 Antibody
  • ENC-1 Antibody
  • ENC1 Antibody
  • ENC1_HUMAN Antibody
  • FLJ39259 Antibody
  • Kelch like 35 Antibody
  • Kelch like 37 Antibody
  • Kelch-like protein 37 Antibody
  • KLHL 35 Antibody
  • KLHL35 Antibody
  • KLHL37 Antibody
  • NRPB Antibody
  • Nuclear matrix protein NRP/B Antibody
  • Nuclear restricted protein BTB domain like (brain) Antibody
  • OTTHUMP00000128235 Antibody
  • OTTHUMP00000222054 Antibody
  • p53 induced gene 10 protein Antibody
  • p53-induced gene 10 protein Antibody
  • PIG 10 Antibody
  • PIG10 Antibody
  • TP53I10 Antibody
  • Tumor protein p53 inducible protein 10 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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