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Anti-ENC-2 Antibody

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产品名称: Anti-ENC-2 Antibody
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简单介绍

Anti-ENC-2 Antibody


Anti-ENC-2 Antibody  的详细介绍
Name: Anti-ENC-2 Antibody
See all ENC-2 primary antibodies
Description: Chicken polyclonal antibody to ENC-2
Applications: E, WB, ICC
Reactivity: Human
Immunogen: Raised against a 14 amino acid peptide near the center of human ENC-2.
Host: Chicken
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity chromatography purified via peptide column
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20˚C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin ligase complex required for translational homeostasis. The BCR(KLHL25) ubiquitin ligase complex acts by mediating ubiquitination of hypophosphorylated EIF4EBP1 (4E-BP1): ubiquitination and subsequent degradation of hypophosphorylated EIF4EBP1 (4E-BP1) probably serves as a homeostatic mechanism to maintain translation and prevent eIF4E inhibition when eIF4E levels are low. The BCR(KLHL25) complex does not target EIF4EBP1 (4E-BP1) when it is hyperphosphorylated or associated with eIF4E.
Database Links:
  • Entrez Gene: 64410 Human
  • SwissProt: Q9H0H3 Human
  • Unigene: 498371 Human
    		•
    Synonyms:
  • 2810402K13Rik Antibody
  • BC027373 Antibody
  • Ectoderm neural cortex protein 2 Antibody
  • Ectoderm-neural cortex protein 2 Antibody
  • ENC 2 Antibody
  • ENC-2 Antibody
  • ENC2 Antibody
  • ENC2_HUMAN Antibody
  • FLJ12587 Antibody
  • FLJ45015 Antibody
  • Kelch like protein 25 Antibody
  • Kelch-like protein 25 Antibody
  • KLHL25 Antibody
  • MGC116251 Antibody
  • MGC36331 Antibody
  • RGD1310815 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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