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Antibodies
Anti-EMMPRIN Antibody
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产品名称:
Anti-EMMPRIN Antibody
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简单介绍
Anti-EMMPRIN
Antibody
Anti-EMMPRIN Antibody
的详细介绍
Overview
Name:
Anti-EMMPRIN
Antibody
See all EMMPRIN primary antibodies
Description:
Rabbit polyclonal antibody to EMMPRIN
Specificity:
EMMPRIN Polyclonal Antibody detects endogenous levels of EMMPRIN protein.
Applications:
WB, IHC, ELISA
Reactivity:
Human, Mouse, Rat
Immunogen:
Synthesized peptide derived from the C-terminal region of human EMMPRIN.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Purification:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration:
1mg / ml
Formulation:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage:
Store at -20?C / 1 year
Target
Function:
Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Tissue Specificity:
Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Post-Translational Modification:
N-glycosylated.
Cellular Location:
Cell membrane. Melanosome.
Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In spermatozoa, localized on the principal piece of caput and in the middle piece during transit in the corpus and cauda epididymides (By similarity).
Database Links:
Entrez Gene: 682?Human
Entrez Gene: 12215?Mouse
Entrez Gene: 25246?Rat
Omim: 109480?Human
SwissProt: P35613?Human
SwissProt: P18572?Mouse
SwissProt: P26453?Rat
Unigene: 501293?Human
Unigene: 431532?Mouse
Unigene: 726?Mouse
Unigene: 2269?Rat
Synonyms:
5A11 antigen Antibody
5F7 Antibody
Basigin Antibody
Basigin (Ok blood group) Antibody
BASI_HUMAN Antibody
Blood brain barrier HT7 antigen Antibody
Bsg Antibody
CD 147 Antibody
CD147 Antibody
CD147 antigen Antibody
Collagenase stimulatory factor Antibody
EMMPRIN Antibody
Extracellular matrix metalloproteinase inducer Antibody
Leukocyte activation antigen M6 Antibody
M 6 Antibody
M6 Antibody
M6 leukocyte activation antigen Antibody
Neurothelin Antibody
OK Antibody
OK blood group Antibody
OK blood group antigen Antibody
TCSF Antibody
Tumor cell derived collagenase stimulatory factor Antibody
Tumor cell-derived collagenase stimulatory factor Antibody
Information:
Target information shown above is from the UniProt Consortium.
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