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Anti-EMMPRIN Antibody

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产品名称: Anti-EMMPRIN Antibody
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简单介绍

Anti-EMMPRIN Antibody


Anti-EMMPRIN Antibody  的详细介绍
Name: Anti-EMMPRIN Antibody
See all EMMPRIN primary antibodies
Description: Rabbit polyclonal antibody to EMMPRIN
Specificity: EMMPRIN Polyclonal Antibody detects endogenous levels of EMMPRIN protein.
Applications: WB, IHC, ELISA
Reactivity: Human, Mouse, Rat
Immunogen: Synthesized peptide derived from the C-terminal region of human EMMPRIN.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Concentration: 1mg / ml
Formulation: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Storage: Store at -20?C / 1 year
Function: Plays an important role in targeting the monocarboxylate transporters SLC16A1, SLC16A3 and SLC16A8 to the plasma membrane. Plays pivotal roles in spermatogenesis, embryo implantation, neural network formation and tumor progression. Stimulates adjacent fibroblasts to produce matrix metalloproteinases (MMPS). Seems to be a receptor for oligomannosidic glycans. In vitro, promotes outgrowth of astrocytic processes.
Tissue Specificity: Present only in vascular endothelium in non-neoplastic regions of the brain, whereas it is present in tumor cells but not in proliferating blood vessels in malignant gliomas.
Post-Translational Modification: N-glycosylated.
Cellular Location: Cell membrane. Melanosome.

Identified by mass spectrometry in melanosome fractions from stage I to stage IV. In spermatozoa, localized on the principal piece of caput and in the middle piece during transit in the corpus and cauda epididymides (By similarity).
Database Links:
  • Entrez Gene: 682?Human
  • Entrez Gene: 12215?Mouse
  • Entrez Gene: 25246?Rat
  • Omim: 109480?Human
  • SwissProt: P35613?Human
  • SwissProt: P18572?Mouse
  • SwissProt: P26453?Rat
  • Unigene: 501293?Human
  • Unigene: 431532?Mouse
  • Unigene: 726?Mouse
  • Unigene: 2269?Rat
  • Synonyms:
  • 5A11 antigen Antibody
  • 5F7 Antibody
  • Basigin Antibody
  • Basigin (Ok blood group) Antibody
  • BASI_HUMAN Antibody
  • Blood brain barrier HT7 antigen Antibody
  • Bsg Antibody
  • CD 147 Antibody
  • CD147 Antibody
  • CD147 antigen Antibody
  • Collagenase stimulatory factor Antibody
  • EMMPRIN Antibody
  • Extracellular matrix metalloproteinase inducer Antibody
  • Leukocyte activation antigen M6 Antibody
  • M 6 Antibody
  • M6 Antibody
  • M6 leukocyte activation antigen Antibody
  • Neurothelin Antibody
  • OK Antibody
  • OK blood group Antibody
  • OK blood group antigen Antibody
  • TCSF Antibody
  • Tumor cell derived collagenase stimulatory factor Antibody
  • Tumor cell-derived collagenase stimulatory factor Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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