产品资料

Anti-Emerin Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-Emerin Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-Emerin Antibody


Anti-Emerin Antibody  的详细介绍
Name: Anti-Emerin Antibody
See all Emerin primary antibodies
Description: Rabbit polyclonal antibody to Emerin
Applications: E, WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Raised against a 19 amino acid peptide from near the amino terminus of human Emerin.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity chromatography purified via peptide column
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Stabilizes and promotes the formation of a nuclear actin cortical network. Stimulates actin polymerization in vitro by binding and stabilizing the pointed end of growing filaments. Inhibits beta-catenin activity by preventing its accumulation in the nucleus. Acts by influencing the nuclear accumulation of beta-catenin through a CRM1-dependent export pathway. Links centrosomes to the nuclear envelope via a microtubule association. Required for proper localization of non-farnesylated prelamin-A/C (By similarity).
Cellular Location: Nucleus inner membrane. Nucleus outer membrane.

Colocalized with BANF1 at the central region of the assembling nuclear rim, near spindle-attachment sites. The accumulation of different intermediates of prelamin-A/C (non-farnesylated or carboxymethylated farnesylated prelamin-A/C) in fibroblasts modify its localization in the nucleus (By similarity).
Database Links:
  • Entrez Gene: 2010?Human
  • Entrez Gene: 13726?Mouse
  • Entrez Gene: 25437?Rat
  • Omim: 300384?Human
  • SwissProt: P50402?Human
  • SwissProt: O08579?Mouse
  • SwissProt: Q63190?Rat
  • Unigene: 522823?Human
  • Unigene: 18892?Mouse
  • Unigene: 10968?Rat
    		•
    Synonyms:
  • EDMD Antibody
  • Emd Antibody
  • EMD_HUMAN Antibody
  • Emerin Antibody
  • Emery Dreifuss muscular dystrophy Antibody
  • STA Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号