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Anti-ELOVL1 Antibody

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产品名称: Anti-ELOVL1 Antibody
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简单介绍

Anti-ELOVL1 Antibody


Anti-ELOVL1 Antibody  的详细介绍
Name: Anti-ELOVL1 Antibody
See all ELOVL1 primary antibodies
Description: Rabbit polyclonal antibody to ELOVL1
Applications: ELISA, IHC, IP, WB
Dilutions: ELISA: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:200; Immunoprecipitation: 1:200; Western Blot: 1:500
Reactivity: Human, Monkey
Immunogen: Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Concentration: 0.5 μg/μl in antibody stabilization buffer
Storage: -20?C for long term storage
Function: Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple biological processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Tissue Specificity: Ubiquitous.
Sequence Similarities: Belongs to the ELO family. ELOVL1 subfamily.
Cellular Location: Endoplasmic reticulum membrane.
Database Links:
  • Entrez Gene: 64834?Human
  • Omim: 611813?Human
  • SwissProt: Q9BW60?Human
  • Unigene: 25597?Human
  • Synonyms:
  • 3 keto acyl CoA synthase ELOVL1 Antibody
  • 3-keto acyl-CoA synthase ELOVL1 Antibody
  • CGI 88 Antibody
  • Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 Antibody
  • Elongation of very long chain fatty acids like 1 Antibody
  • Elongation of very long chain fatty acids protein 1 Antibody
  • ELOV1_HUMAN Antibody
  • ELOVL 1 Antibody
  • ELOVL FA elongase 1 Antibody
  • ELOVL fatty acid elongase 1 Antibody
  • ELOVL1 Antibody
  • Ssc1 Antibody
  • Ssc1, mouse, homolog of Antibody
  • very long chain 3 oxoacyl CoA synthase 1 Antibody
  • Very-long-chain 3-oxoacyl-CoA synthase 1 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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