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Antibodies
Anti-ELOVL1 Antibody
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产品名称:
Anti-ELOVL1 Antibody
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简单介绍
Anti-ELOVL1
Antibody
Anti-ELOVL1 Antibody
的详细介绍
Overview
Name:
Anti-ELOVL1
Antibody
See all ELOVL1 primary antibodies
Description:
Rabbit polyclonal antibody to ELOVL1
Applications:
ELISA, IHC, IP, WB
Dilutions:
ELISA: 1:10,000; ELISA: 1:10,000; Immunoprecipitation: 1:200; Immunoprecipitation: 1:200; Western Blot: 1:500
Reactivity:
Human, Monkey
Immunogen:
Synthetic peptide taken within amino acid region 148-198 on human Elongation of very long chain fatty acids protein 1.
Host:
Rabbit
Clonality:
Polyclonal
Conjugate:
Unconjugated
Concentration:
0.5 μg/μl in antibody stabilization buffer
Storage:
-20?C for long term storage
Target
Function:
Catalyzes the first and rate-limiting reaction of the four that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process, allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids/VLCFAs per cycle. Condensing enzyme that exhibits activity toward saturated C18 to C26 acyl-CoA substrates, with the highest activity towards C22:0 acyl-CoA. May participate in the production of both saturated and monounsaturated VLCFAs of different chain lengths that are involved in multiple
biolog
ical processes as precursors of membrane lipids and lipid mediators. Important for saturated C24:0 and monounsaturated C24:1 sphingolipid synthesis. Indirectly inhibits RPE65 via production of VLCFAs.
Tissue Specificity:
Ubiquitous.
Sequence Similarities:
Belongs to the ELO family. ELOVL1 subfamily.
Cellular Location:
Endoplasmic reticulum membrane.
Database Links:
Entrez Gene: 64834?Human
Omim: 611813?Human
SwissProt: Q9BW60?Human
Unigene: 25597?Human
Synonyms:
3 keto acyl CoA synthase ELOVL1 Antibody
3-keto acyl-CoA synthase ELOVL1 Antibody
CGI 88 Antibody
Elongation of very long chain fatty acids (FEN1/Elo2 SUR4/Elo3 yeast) like 1 Antibody
Elongation of very long chain fatty acids like 1 Antibody
Elongation of very long chain fatty acids protein 1 Antibody
ELOV1_HUMAN Antibody
ELOVL 1 Antibody
ELOVL FA elongase 1 Antibody
ELOVL fatty acid elongase 1 Antibody
ELOVL1 Antibody
Ssc1 Antibody
Ssc1, mouse, homolog of Antibody
very long chain 3 oxoacyl CoA synthase 1 Antibody
Very-long-chain 3-oxoacyl-CoA synthase 1 Antibody
Information:
Target information shown above is from the UniProt Consortium.
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