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Anti-Elk1 (S383) Antibody

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产品名称: Anti-Elk1 (S383) Antibody
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Anti-Elk1 (S383) Antibody


Anti-Elk1 (S383) Antibody  的详细介绍
Name: Anti-Elk1 (S383) Antibody
See all Elk1 primary antibodies
Description: Rabbit polyclonal antibody to Elk1 (S383)
Specificity: Elk1 (S383) pAb detects endogenous levels of Elk1 protein.
Applications: WB, IHC, IP
Reactivity: Human, Mouse, Rat
Immunogen: Synthetic peptide, corresponding to amino acids 350-400 of Human Elk1.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Molecular Weight: ~ 45 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Product Form: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Function: Transcription factor that binds to purine-rich DNA sequences. Forms a ternary complex with SRF and the ETS and SRF motifs of the serum response element (SRE) on the promoter region of immediate early genes such as FOS and IER2. Induces target gene transcription upon JNK-signaling pathway stimulation (By similarity).
Tissue Specificity: Lung and testis.
Sequence Similarities: Belongs to the ETS family.
Post-Translational Modification: Sumoylation represses transcriptional activator activity as it results in recruitment of HDAC2 to target gene promoters which leads to decreased histone acetylation and reduced transactivator activity. It also regulates nuclear retention.
Cellular Location: Nucleus.
Database Links:
  • Entrez Gene: 2002?Human
  • Entrez Gene: 13712?Mouse
  • Entrez Gene: 314436?Rat
  • Omim: 311040?Human
  • SwissProt: P19419?Human
  • SwissProt: P41969?Mouse
  • SwissProt: A4GTP4?Rat
  • Unigene: 181128?Human
  • Unigene: 405823?Mouse
  • Unigene: 203416?Rat
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    Synonyms:
  • ELK 1 Antibody
  • ELK1 Antibody
  • ELK1 member of ETS oncogene family Antibody
  • ELK1 protein Antibody
  • ELK1, ETS transcription factor Antibody
  • ELK1_HUMAN Antibody
  • ELK2 member of ETS oncogene family Antibody
  • ETS domain containing protein Elk 1 Antibody
  • ETS domain containing protein Elk1 Antibody
  • ETS domain protein Elk1 Antibody
  • ETS domain-containing protein Elk-1 Antibody
  • ETS like gene 1 Antibody
  • Member of ETS oncogene family Antibody
  • Oncogene Elk1 Antibody
  • Tyrosine kinase (ELK1) oncogene Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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