产品资料

Anti-EIF3H Antibody

如果您对该产品感兴趣的话,可以
产品名称: Anti-EIF3H Antibody
产品型号:
产品展商: 其它品牌
产品文档: 无相关文档

简单介绍

Anti-EIF3H Antibody


Anti-EIF3H Antibody  的详细介绍
Name: Anti-EIF3H Antibody
See all EIF3H primary antibodies
Description: Rabbit polyclonal antibody to EIF3H
Specificity: The antibody detects endogenous levels of total EIF3H protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to residues near the C terminal of human eukaryotic translation initiation factor 3, subunit H
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1.7mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis (PubMed:17581632, PubMed:25849773, PubMed:27462815). The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S pre-initiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation (PubMed:17581632). The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation, including cell cycling, differentiation and apoptosis, and uses different modes of RNA stem-loop binding to exert either translational activation or repression (PubMed:25849773).
Sequence Similarities: Belongs to the eIF-3 subunit H family.
Cellular Location: Cytoplasm.
Database Links:
  • Entrez Gene: 8667?Human
  • Omim: 603912?Human
  • SwissProt: O15372?Human
  • Unigene: 492599?Human
    		•
    Synonyms:
  • eIF-3-gamma Antibody
  • eIF3 gamma Antibody
  • eIF3 p40 Antibody
  • eIF3 p40 subunit Antibody
  • eIF3h Antibody
  • EIF3H_HUMAN Antibody
  • EIF3S3 Antibody
  • Eukaryotic translation initiation factor 3 subunit 3 Antibody
  • Eukaryotic translation initiation factor 3 subunit H Antibody
  • MGC102958 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
    产品留言
    标题
    联系人
    联系电话
    内容
    验证码
    点击换一张
    注：1.可以使用快捷键Alt+S或Ctrl+Enter发送信息!
    2.如有必要,请您留下您的详细联系方式!

    沪公网安备 31011202007337号