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Anti-EIF2C3 Antibody

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产品名称: Anti-EIF2C3 Antibody
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简单介绍

Anti-EIF2C3 Antibody


Anti-EIF2C3 Antibody  的详细介绍
Name: Anti-EIF2C3 Antibody
See all EIF2C3 primary antibodies
Description: Rabbit polyclonal antibody to EIF2C3
Applications: ELISA, WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Rabbit polyclonal EIF2C3(1) antibody was raised against a peptide from the intermediate residues of human EIF2C3 protein.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity purified
Concentration: 1.0mg / ml
Formulation: PBS, pH 7.4 with 0.02% sodium azide.
Storage: This product is stable for several weeks at 4?C as an undiluted liquid. Dilute only prior to immediate use. For extended storage, aliquot contents and freeze at -20?C or below. Avoid cycles of freezing and thawing. Expiration date is one (1) year from date of receipt.
Function: Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs. Proposed to be involved in stabilization of small RNA derivates (riRNA) derived from processed RNA polymerase III-transcribed Alu repeats containing a DR2 retinoic acid response element (RARE) in stem cells and in the subsequent riRNA-dependent degradation of a subset of RNA polymerase II-transcribed coding mRNAs by recruiting a mRNA decapping complex involving EDC4.
Sequence Similarities: Belongs to the argonaute family. Ago subfamily.
Cellular Location: Cytoplasm > P-body.
Database Links:
  • Entrez Gene: 192669?Human
  • Entrez Gene: 214150?Mouse
  • Entrez Gene: 313593?Rat
  • Omim: 607355?Human
  • SwissProt: Q9H9G7?Human
  • SwissProt: Q8CJF9?Mouse
  • Unigene: 657659?Human
  • Unigene: 440915?Mouse
  • Unigene: 482388?Mouse
  • Unigene: 483093?Mouse
  • Unigene: 92025?Rat
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    Synonyms:
  • 5730550L01Rik Antibody
  • Ago 3 Antibody
  • Ago3 Antibody
  • AGO3_HUMAN Antibody
  • argonaute 3 Antibody
  • Argonaute 3 / eIF2C 3 Antibody
  • Argonaute3 Antibody
  • eIF 2C 3 Antibody
  • eIF-2C 3 Antibody
  • eIF2C 3 Antibody
  • Eif2c3 Antibody
  • EIF2C3 protein Antibody
  • Eukaryotic translation initiation factor 2C 3 Antibody
  • Eukaryotic translation initiation factor 2C3 Antibody
  • FLJ12765 Antibody
  • hAgo3 Antibody
  • MGC86946 Antibody
  • Protein argonaute-3 Antibody
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    Information: Target information shown above is from the UniProt Consortium.
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