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Anti-EGF Antibody

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产品名称: Anti-EGF Antibody
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简单介绍

Anti-EGF Antibody


Anti-EGF Antibody  的详细介绍
Name: Anti-EGF Antibody
See all EGF primary antibodies
Description: Rabbit polyclonal antibody to EGF.
Applications: WB, IHC
Dilutions: WB: 1:500 - 1:2000, IHC: 1:50 - 1:100.
Reactivity: Human, Mouse
Immunogen: Recombinant protein of human EGF.
Protein Length: 1207
Host: Rabbit
Clonality: Polyclonal
Isotype: IgG
Conjugate: Unconjugated
Purification: Affinity purification.
Product Form: Liquid
Formulation: Supplied in Phosphate Buffered Saline, pH 7.30, with 0.02% Sodium Azide and 50% Glycerol.
Storage: Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles.
Function: EGF stimulates the growth of various epidermal and epithelial tissues in vivo and in vitro and of some fibroblasts in cell culture. Magnesiotropic hormone that stimulates magnesium reabsorption in the renal distal convoluted tubule via engagement of EGFR and activation of the magnesium channel TRPM6. Can induce neurite outgrowth in motoneurons of the pond snail Lymnaea stagnalis in vitro (PubMed:10964941).
Tissue Specificity: Expressed in kidney, salivary gland, cerebrum and prostate.
Involvement in Disease: Hypomagnesemia 4: A disorder characterized by massive renal hypomagnesemia and normal levels of serum calcium and calcium excretion. Clinical features include seizures, mild-to moderate psychomotor retardation, and brisk tendon reflexes.
Post-Translational Modification: O-glycosylated with core 1-like and core 2-like glycans. It is uncertain if Ser-954 or Thr-955 is O-glycosylated. The modification here shows glycan heterogeneity: HexHexNAc (major) and Hex2HexNAc2 (minor).
Cellular Location: Membrane.
Database Links:
  • Entrez Gene: 1950?Human
  • Entrez Gene: 13645?Mouse
  • Omim: 131530?Human
  • SwissProt: P01133?Human
  • SwissProt: P01132?Mouse
  • Unigene: 419815?Human
  • Unigene: 252481?Mouse
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    Synonyms:
  • AI790464 Antibody
  • Beta urogastrone Antibody
  • beta-urogastrone Antibody
  • EGF Antibody
  • EGF_HUMAN Antibody
  • Epidermal growth factor Antibody
  • HOMG4 Antibody
  • OTTHUMP00000219721 Antibody
  • OTTHUMP00000219722 Antibody
  • Pro epidermal growth factor Antibody
  • Pro epidermal growth factor precursor (EGF) Antibody
  • URG Antibody
  • Urogastrone Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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