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Anti-ECE2 Antibody

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产品名称: Anti-ECE2 Antibody
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Anti-ECE2 Antibody


Anti-ECE2 Antibody  的详细介绍
Name: Anti-ECE2 Antibody
See all ECE2 primary antibodies
Description: Rabbit polyclonal antibody to ECE2
Specificity: The antibody detects endogenous levels of total ECE2 protein.
Applications: IHC
Reactivity: Human
Immunogen: Fusion protein corresponding to a region derived from internal residues of human endothelin converting enzyme 2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Antigen affinity purification.
Concentration: 1mg / ml
Formulation: Rabbit IgG in pH7.3 PBS, 0.05% NaN3, 50% Glycerol.
Storage: Store at -20?C
Function: Converts big endothelin-1 to endothelin-1. Also involved in the processing of various neuroendocrine peptides, including neurotensin, angiotensin I, substance P, proenkephalin-derived peptides, and prodynorphin-derived peptides. May limit beta-amyloid peptide accumulation in brain. May also have methyltransferase activity.
Tissue Specificity: Expressed in brain. Strongly down-regulated in inferior parietal lobe from Alzheimer disease patients (at protein level).
Sequence Similarities: In the N-terminal section; belongs to the methyltransferase superfamily.
Cellular Location: Golgi apparatus membrane. Cytoplasmic granule membrane.
Database Links:
  • Entrez Gene: 9718?Human
  • Omim: 610145?Human
  • SwissProt: O60344?Human
  • Unigene: 146161?Human
  • Synonyms:
  • ECE 2 Antibody
  • ECE-2 Antibody
  • ECE2 Antibody
  • ECE2_HUMAN Antibody
  • Endothelin converting enzyme 2 Antibody
  • Endothelin-converting enzyme 2 region Antibody
  • Hypothetical protein MGC2408 Antibody
  • KIAA0604 Antibody
  • MGC17664 Antibody
  • MGC78487 Antibody
  • Information: Target information shown above is from the UniProt Consortium.
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