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Anti-EBI3 Antibody

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产品名称: Anti-EBI3 Antibody
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简单介绍

Anti-EBI3 Antibody


Anti-EBI3 Antibody  的详细介绍
Name: Anti-EBI3 Antibody
See all EBI3 primary antibodies
Description: Rabbit polyclonal antibody to EBI3
Applications: E, WB, IHC
Reactivity: Human, Mouse, Rat
Immunogen: Raised against a 16 amino acid peptide from near the center of human EBI3.
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Affinity chromatography purified via peptide column
Formulation: Supplied in PBS containing 0.02% sodium azide.
Storage: Can be stored at -20?C, stable for one year. As with all antibodies care should be taken to avoid repeated freeze thaw cycles. Antibodies should not be exposed to prolonged high temperatures.
Function: Associates with IL27 to form the IL-27 interleukin, a heterodimeric cytokine which functions in innate immunity. IL-27 has pro- and anti-inflammatory properties, that can regulate T-helper cell development, suppress T-cell proliferation, stimulate cytotoxic T-cell activity, induce isotype switching in B-cells, and that has diverse effects on innate immune cells. Among its target cells are CD4 T-helper cells which can differentiate in type 1 effector cells (TH1), type 2 effector cells (TH2) and IL17 producing helper T-cells (TH17). It drives rapid clonal expansion of naive but not memory CD4 T-cells. It also strongly synergizes with IL-12 to trigger interferon-gamma/IFN-gamma production of naive CD4 T-cells, binds to the cytokine receptor WSX-1/TCCR. Another important role of IL-27 is its antitumor activity as well as its antiangiogenic activity with activation of production of antiangiogenic chemokines.
Sequence Similarities: Belongs to the type I cytokine receptor family. Type 3 subfamily.
Cellular Location: Secreted.
Database Links:
  • Entrez Gene: 10148?Human
  • Entrez Gene: 50498?Mouse
  • Entrez Gene: 680609?Rat
  • Omim: 605816?Human
  • SwissProt: Q14213?Human
  • SwissProt: O35228?Mouse
  • Unigene: 501452?Human
  • Unigene: 256798?Mouse
    		•
    Synonyms:
  • cytokine receptor Antibody
  • EBI3 Antibody
  • EBV induced gene 3 protein Antibody
  • EBV-induced gene 3 protein Antibody
  • Epstein Barr virus induced 3 Antibody
  • Epstein Barr virus induced gene 3 Antibody
  • Epstein Barr virus induced gene 3 protein Antibody
  • Epstein-Barr virus-induced gene 3 protein Antibody
  • IL 27 subunit beta Antibody
  • IL 27B Antibody
  • IL-27 subunit beta Antibody
  • IL-27B Antibody
  • IL27 subunit Antibody
  • IL27 subunit beta Antibody
  • IL27B Antibody
  • IL27B_HUMAN Antibody
  • IL35 subunit Antibody
  • interleukin 27 subunit beta Antibody
  • Interleukin-27 subunit beta Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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