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Anti-DYNC1I2 Antibody

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产品名称: Anti-DYNC1I2 Antibody
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Anti-DYNC1I2 Antibody


Anti-DYNC1I2 Antibody  的详细介绍
Name: Anti-DYNC1I2 Antibody
See all DYNC1I2 primary antibodies
Description: Rabbit polyclonal antibody to DYNC1I2
Applications: WB, IF
Reactivity: Human
Immunogen: Recombinant protein fragment contain a sequence corresponding to a region within amino acids 129 and 376 of human DYNC1I2
Host: Rabbit
Clonality: Polyclonal
Conjugate: Unconjugated
Purification: Purified by antigen-affinity chromatography.
Formulation: Supplied in 0.1M Tris-buffered saline with 10% Glycerol (pH7.0). 0.01% Thimerosal was added as a preservative.
Storage: Store at -20˚C for long term preservation (recommended). Store at 4˚C for short term use.
Function: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. The intermediate chains mediate the binding of dynein to dynactin via its 150 kDa component (p150-glued) DCNT1. Involved in membrane-transport, such as Golgi apparatus, late endosomes and lysosomes.
Sequence Similarities: Belongs to the dynein intermediate chain family.
Post-Translational Modification: The phosphorylation status of Ser-90 appears to be involved in dynactin-dependent target binding.
Cellular Location: Cytoplasm > Cytoskeleton.
Database Links:
  • Entrez Gene: 1781 Human
  • Omim: 603331 Human
  • SwissProt: Q13409 Human
  • Unigene: 546250 Human
    		•
    Synonyms:
  • Cytoplasmic dynein 1 intermediate chain 2 Antibody
  • Cytoplasmic dynein intermediate chain 2 Antibody
  • cytosolic Antibody
  • DC1I2_HUMAN Antibody
  • DH IC 2 Antibody
  • DH IC-2 Antibody
  • DNCI2 Antibody
  • DNCIC2 Antibody
  • DYNC1I2 Antibody
  • Dynein intermediate chain 2 Antibody
  • Dynein intermediate chain 2, cytosolic Antibody
  • Dynein, cytoplasmic, intermediate polypeptide 2 Antibody
  • IC2 Antibody
    		•
    Information: Target information shown above is from the UniProt Consortium.
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